学術論文 |
- "Functional analysis of a S-adenosylmethionine-insensitive methylenetetrahydrofolate reductase identified in methionine-accumulating yeast mutants," Bioscience, Biotechnology, and Biochemistry, vol.89, no.1, pp124-132, 2025.1.1
- Shota Isogai, Akira Nishimura, Akiko Inoue, Shino Sonohara, Takashi Tsugukuni, Hiroshi Takagi
- "unctional analysis of a S-adenosylmethionine-insensitive methylenetetrahydrofolate reductase identified in methionine-accumulating yeast mutants.," Bioscience, Biotechnology, and Biochemistry, vol.89, no.1, pp124-132, 4 Nov. 2024
- Shota Isogai, Akira Nishimura, Akiko Inoue, Shino Sonohara, Takashi Tsugukuni, Hiroshi Takagi
- "Enhancing freezing stress tolerance through regulation of the ubiquitin-proteasome system in Saccharomyces cerevisiae.," Fermentation, vol.10, no.6, pp318, 15 Jun. 2024
- Tanahashi Ryoya, Akira Nishimura, Kyoyuki Kan, Natsumi Ishizaki, Shiho Fujishima, Hisanori Endo, Hiroshi Takagi
- "Functional analysis of feedback inhibition-insensitive aspartate kinase identified in a threonine-accumulating mutant of Saccharomyces cerevisiae.," Appl. Environ. Microbiol., vol.90, ppe00155-24, 8 Mar. 2024
- Shota Isogai, Akira Nishimura, Akiko Inoue, Shino Sonohara, Takashi Tsugukuni, Tomoyuki Okada, Hiroshi Takagi
- "Regulations and functions of proline utilization in yeast Saccharomyces cerevisiae,," Bioscience, Biotechnology, and Biochemistry,, vol.88, no.2, pp131-137, Feb. 2024
- Akira Nishimura
- "The arginine transporter Can1 negatively regulates biofilm formation in yeasts. ," Front. Microbiol., no.15, pp1419530, 5 Jan. 2024
- Akira Nishimura, Tanahashi Ryoya, Kazuki Nakagami, Yuto Morioka, Hiroshi Takagi
- "Longevity control by supersulfide-mediated mitochondrial respiration and regulation of protein quality," Redox Biol, vol.69, pp103018, 3 Jan. 2024
- Akira Nishimura, Yoon S, Matsunaga T, Ida T, Jung M, Ogata S, Morita M, Yoshitake J, Unno Y, Barayeu U, Takata T, Takagi H, Motohashi H, van der Vliet A, Akaike T
- "Isolation of yeast strains with higher proline uptake and their applications to beer fermentation.," J. Fungi, vol.9, pp1137, 24 Nov. 2023
- Tanahashi Ryoya, Akira Nishimura, Minh Nguyen, Irnayuli Sitepu, Glen Fox, Kyria Boundy-Mills, Hiroshi Takagi
- "PKA-Msn2/4-Shy1 cascade controls inhibition of proline utilization under wine fermentation models," J Biosci Bioeng, vol.136, pp438-442, 7 Nov. 2023
- Akira Nishimura, Tanahashi Ryoya, Nakazawa H, Oi T, Mima M, Takagi H
- "PKA-Msn2/4-Shy1 cascade controls inhibition of proline utilization under wine fermentation models.," J. Biosci. Bioeng., vol.136, pp438-442, 7 Nov. 2023
- Akira Nishimura, Ryoya Tanahashi, Hayate Nakazawa, Tomoki Oi, Misaki Mima, Hiroshi Takagi
- "Supersulfide catalysis for nitric oxide and aldehyde metabolism," SCIENCE ADVANCES, vol.9, no.33, ppeadg8631, 19 Aug. 2023
- Kasamatsu S, Akira Nishimura, Alam M, Morita M, Shimoda K, Matsunaga T, Jung M, Ogata S, Barayeu U, Ida T, Nishida M, Nishimura A, Motohashi H, Akaike T
- "Large-scale screening of yeast strains that can utilize proline," Biosci. Biotech. Biochem, vol.87, pp358-362, 3 Mar. 2023
- Tanahashi Ryoya, Akira Nishimura, Minh Nguyen, Irnayuli Sitepu, Glen Fox, Kyria Boundy-Mills, Hiroshi Takagi
 [ doi:10.1093/bbb/zbac202 ]
- "Plasmid-free CRISPR/Cas9 genome editing in Saccharomyces cerevisiae.," Biosci. Biotech. Biochem., vol.87, pp458-462, Mar. 2023
- A. Nishimura, R. Tanahashi, T. Oi, K. Kan, H. Takagi
- "Identification of an arginine transporter in Candida glabrata. J. Gen. Appl. Microbiol.," J. Gen. Appl. Microbiol., in press, Mar. 2023
- A. Nishimura, R. Tanahashi, K. Nakagami, Y. Morioka, H. Takagi
[ doi:10.2323/jgam.2023.03.003 ]
- "Synthesis of sulfides and persulfides is not impeded by disruption of three canonical enzymes in sulfur metabolism. Antioxidants," Antioxidants, vol.12, no.4, pp868, 31 Jan. 2023
- Abidin QHZ, Ida T, Morita M, Matsunaga T, Nishimura A, Jung M, Hassan N, Takata T, Ishii I, Kruger W, Wang R, Motohashi H, Tsutsui M, Akaike T
- "Improvement of valine and isobutanol production in sake yeast by Ala31Thr substitution in the regulatory subunit of acetohydroxy acid synthase.," FEMS Yeast Res, vol.23, ppfoad012, 4 Jan. 2023
- S. Isogai, A. Nishimura, N. Murakami, N. Hotta, A. Kotaka, Y. Toyokawa, H. Ishida, H. Takagi
- "The arginine transporter Can1 acts as a transceptor for regulation of proline utilization in the yeast Saccharomyces cerevisiae. ," Yeast, vol.40, pp333-348, 27 Dec. 2022
- Tanahashi Ryoya, Akira Nishimura, Fumika Morita, Hayate Nakazawa, Atsuki Taniguchi, Kazuki Ichikawa, Kazuki Nakagami, Kyria Boundy-Mills, Hiroshi Takagi
- "Supersulfide catalysis for nitric oxide and aldehyde metabolism.," SCIENCE ADVANCES, vol.9, no.33, ppeadg8631, 19 Aug. 2022
- Kasamatsu S*, Nishimura A*, Alam M*, Morita M*, Shimoda K, Matsunaga T, Jung M, Ogata S, Barayeu U, Ida T, Nishida M, Nishimura A, Motohashi H, Akaike T
- "Arginine inhibits Saccharomyces cerevisiae biofilm formation by inducing endocytosis of the arginine transporter Can1. ," Biosci. Biotech. Biochem., vol.86, pp1300-1307, 24 Jun. 2022
- Akira Nishimura, Kazuki Nakagami, Kyoyuki Kan, Fumika Morita, Hiroshi Takagi
- "The Cdc25/Ras/cAMP-dependent protein kinase A signaling pathway regulates proline utilization in wine yeast Saccharomyces cerevisiae under a wine fermentation model. Biosci. Biotech. Biochem.,," Biosci. Biotech. Biochem., vol.86, pp1318-1326, 24 Jun. 2022
- Akira Nishimura, Kazuki Ichikawa, Hayate Nakazawa, Tanahashi Ryoya, Fumika Morita, Irnayuli Sitepu, Kyria Boundy-Mills, Glen Fox, Hiroshi Takagi
- "機能性アミノ酸高含有酵母による酒類の高付加価値化. 「発酵・醸造食品の最前線II」（監修 北本勝ひこ）," シーエムシー出版, pp102-116, 2022.3.10
- 高木博史, 西村 明, 磯貝章太
- "「アミノ酸機能工学」による酵母の高機能開発とその産業応用," 科学と工業, vol.96, no.3, pp57-66, 2022.3
- 高木博史, 磯貝章太, 西村 明
- "High-level production of isoleucine and fusel alcohol by expression of the feedback inhibition-insensitive threonine deaminase in Saccharomyces cerevisiae.," Appl. Environ. Microbiol., vol.88, ppe02130-21, 12 Jan. 2022
- Shota Isogai, Akira Nishimura, Atsushi Kotaka, Naoyuki Murakami, Natsuki Hotta, Hiroki Ishida, Hiroshi Takagi
[ doi:10.1128/AEM.02130-21 ]
- "GRIM-19 is a target of mycobacterial Zn2+ metalloprotease 1 and indispensable for NLRP3 inflammasome activation.," FASEB J., vol.36, no.1, ppe22096, Jan. 2022
- Tomomi Kurane, Tetsuro Matsunaga, Tomoaki Ida, Kazuko Sawada, Akira Nishimura, Masayuki Fukui, Masayuki Umemura, Masaaki Nakayama, Naoya Ohara, Sohkichi Matsumoto, Takaaki Akaike, Goro Matsuzaki, Giichi Takaesu
[ doi:10.1096/fj.202101074RR ]
- "Isolation and analysis of a sake yeast mutant with phenylalanine accumulation.," J. Ind. Microbiol. Biotechnol., vol.49, ppkuab085, 12 Nov. 2021
- Akira Nishimura, Shota Isogai, Naoyuki Murakami, Natsuki Hotta, Atsushi Kotaka, Kengo Matsumura, Yoji Hata, Hiroki Ishida, Hiroshi Takagi
[ doi:10.1093/jimb/kuab085 ]
- "寿命・老化における超硫黄分子の役割," 生化学, vol.93, pp717-722, 2021.10.25
- 西村 明
- "Role of Gln79 in feedback inhibition of the yeast γ-glutamyl kinase by proline.," Microorganisms, vol.9, no.9, pp1902, Sep. 2021
- Akira Nishimura, Yurie Takasaki, Shota Isogai, Yoichi Toyokawa, Ryoya Tanahashi, Hiroshi Takagi
 [ NAISTレポジトリ ] [ doi:10.3390/microorganisms9091902 ]
- "Longevity regulation by proline oxidation in yeast.," Microorganisms, vol.9, no.8, pp1650, Aug. 2021
- Akira Nishimura, Yuki Yoshikawa, Kazuki Ichikawa, Tetsuma Takemoto, Ryoya Tanahashi, Hiroshi Takagi
[ NAISTレポジトリ ] [ doi:10.3390/microorganisms9081650. ]
- "High-level production of lysine in the yeast Saccharomyces cerevisiae by rational design of homocitrate synthase.," Appl. Environ. Microbiol., vol.87(15),e0060021, May. 2021
- S. Isogai, T. Matsushita, H. Imanishi, J. Koonthongkaew, Y. Toyokawa, A. Nishimura, X. Yi, R. Kazlauskas, H. Takagi
- "酵母におけるプロリンの新しい生理機能と代謝調節機構," 生化学, vol.93, pp203-211, 2021.4.25
- 西村 明, 高崎友里恵, 高木博史
- "Downregulation of the broad-specificity amino acid permease Agp1 mediated by the ubiquitin ligase Rsp5 and the arrestin-like protein Bul1 in yeast.," Biosci. Biotech. Biochem., vol.85, pp1266-1274, 23 Feb. 2021
- Ryoya Tanahashi, Tomonori Matsushita, Akira Nishimura, Hiroshi Takagi
- "The C2 domain of the ubiquitin ligase Rsp5 is required for ubiquitination of the endocytic protein Rvs167 upon change of nitrogen source.," FEMS Yeast Res., vol.20, ppfoaa058, 14 Oct. 2020
- Ryoya Tanahashi, Tira Siti Nur Afiah, Akira Nishimura, Daisuke Watanabe, Hiroshi Takagi
[ doi:10.1093/femsyr/foaa058 ]
- "Effects of a novel variant of the yeast γ-glutamyl kinase Pro1 on its enzymatic activity and sake brewing.," J. Ind. Microbiol. Biotechnol., vol.47, pp715-723, Aug. 2020
- Naoyuki Murakami, Atsushi Kotaka, Shota Isogai, Keiko Ashida, Akira Nishimura, Kengo Matsumura, Yoji Hata, Hiroki Ishida, Hiroshi Takagi
[ NAISTレポジトリ ] [ doi:10.1007/s10295-020-02297-1 ]
- "The yeast α-arrestin Art3 is a key regulator for arginine-induced endocytosis of the high-affinity proline transporter Put4.," Biochem. Biophys. Res. Commun., no.531, pp416-421, Aug. 2020
- Akira Nishimura, Ryoya Tanahashi, Hiroshi Takagi
[ NAISTレポジトリ ] [ doi:10.1016/j.bbrc.2020.07.117 ]
- "Inhibitory effect of arginine on proline utilization in Saccharomyces cerevisiae.," Yeast, vol.37, pp531-540, Jun. 2020
- Akira Nishimura, Tsubasa Tanikawa, Hiroshi Takagi
[ NAISTレポジトリ ] [ doi:10.1002/yea.3504. ]
- "Control of protein function through oxidation and reduction of persulfidated states. ," Sci Adv, vol.6, Jan. 2020
- Dóka É, Ida T, Dagnell M, Abiko Y, Cong NL, Balog N, Takata T, Espinosa B, Akira Nishimura, Cheng Q, Funato Y, Miki H, Fukuto J, Prigge JR, Schmidt EE, Arnér ES, Kumagai Y, Akaike T, Nagy P
[ doi:10.1126/sciadv.aax8358, 2020 ]
- "Mitochondrial cysteinyl-tRNA synthetase is expressed via alternative transcriptional initiation regulated by energy metabolism in yeast.," J. Biol. Chem., vol.294, pp13781-13788, Oct. 2019
- R. Nishimura, R. Nasuno, Y. Yoshikawa, M. Jung, T. Ida, T. Matsunaga, M. Morita, H. Takagi, H. Motohashi, T. Akaike
- "CRMP-2 induces axons in cultured hippocampal neurons. ," Nat Neurosci, vol.4, no.8, pp781-782, Aug. 2001
- Inagaki, N, Chihara, K, Arimura, N, Menager, C, Kawano, Y, Matsuo, N, Nishimura, T, Amano, M, Kaibuchi, K.
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