加藤 順也

所属 研究推進機構 研究推進部門
職位 特任教授
学位
研究室 研究推進機構
研究キーワード
研究分野
ライフサイエンス / 腫瘍生物学 /
研究室概要
学術論文
"PGV-1 permanently arrests HepG2 cells in M phase and inhibits liver carcinogenesis in DMH-induced rats," Journal of Applied Pharmaceutical Science, vol.13, no.8, pp204-211, 4 Aug. 2023
Dhania Novitasari, Jun-ya Kato, Dyaningtyas Dewi Pamungkas Putri, Febri Wulandari, Sitarina Widyarini, Ummi Maryam Zulfin, Dhiya Ulhaq Salsabila, Edy Meiyanto
"Chemoprevention curcumin analog 1.1 promotes metaphase arrest and enhances intracellular reactive oxygen species levels on TNBC MDA-MB-231 and HER2-positive HCC1954 cells," Research in Pharmaceutical Sciences, vol.18, no.4, pp358-370, 1 Jul. 2023
Dhania Novitasari, Riris Istighfari Jenie, Jun-ya Kato, Edy Meiyanto
"Curcumin analogs PGV-1 and CCA-1.1 induce cell cycle arrest in human hepatocellular carcinoma cells with overexpressed MYCN," The Indonesian Biomedical Journal, vol.15, no.2, pp141-149, 18 Apr. 2023
Moordiani Moordiani, Dhania Novitasari, Ratna Asmah Susidarti, Jun-ya Kato, Edy Meiyanto
"Network Pharmacological Analysis Identifies the Curcumin Analog CCA-1.1 Targeting Mitosis Regulatory Process in HER2-Positive Breast Cancer.," ndonesian Journal of Pharmacy, vol.34, no.1, 1 Jan. 2023
Dhania Novitasari, Riris Istighfari Jenie, Jun-ya Kato, Edy Meiyanto
"Preclinical evaluation of pentagamavunone-1 as monotherapy and combination therapy for pancreatic cancer in multiple xenograft models," Scientific Reports, vol.12, no.1, pp22419, 27 Dec. 2022
Naoki Kamitani, Ikuko Nakamae, Noriko Yoneda-Kato, Jun-ya Kato, Masayuki Sho
[ doi:10.1038/s41598-022-26863-y ]
"Preparation and cytotoxic evaluation of PGV-1 derivative, CCA-1.1, as a new curcumin analog with improved-physicochemical and pharmacological properties," Advanced pharmaceutical bulletin, vol.12, no.3, pp603, May. 2022
Rohmad Yudi Utomo, Febri Wulandari, Dhania Novitasari, Beni Lestari, Ratna Asmah Susidarti, Riris Istighfari Jenie, Jun-ya Kato, Sardjiman Sardjiman, Edy Meiyanto
"CCA-1.1 exerts cytotoxic activities against TNBC and HER2-enriched breast cancer: in vitro and bioinformatic studies," CANCER SCIENCE, vol.113, pp1030, 1 Feb. 2022
Novitasari Dhania, Febri Wulandari, Rohmad Y Utomo, Riris I Jenie, Jun-ya Kato, Edy Meiyanto
"Targeting Abnormal Cell Cycle in Cancer: A Preface to the Special Issue," Onco, vol.2, no.1, pp34-35, 13 Jan. 2022
Chiaki Takahashi, Jun-ya Kato
"The integrative bioinformatic analysis deciphers the predicted molecular target gene and pathway from curcumin derivative CCA-1.1 against triple-negative breast cancer (TNBC)," Journal of the Egyptian National Cancer Institute, vol.33, no.1, pp1-10, Dec. 2021
Dhania Novitasari, Riris Istighfari Jenie, Jun-ya Kato, Edy Meiyanto
"A new curcumin analog, CCA-1.1, induces cell death and cell cycle arrest in WiDr colon cancer cells via ROS generation," Journal of Applied Pharmaceutical Science, vol.11, no.10, pp99-105, 3 Oct. 2021
Febri Wulandari, Muthi Ikawati, Mitsunori Kirihata, Jun-ya Kato, Edy Meiyanto
"The Two Mono-Carbonyl Curcumin Analogs, PGV-1 and CCA-1.1: The Chemopreventive Activity Against DMH-Induced Colorectal Cancer Rat and Proteins Target Candidate Involved," Research Square, 1 Oct. 2021
Febri Wulandari, Mitsunori Kirihata, Sitarina Widyarini, Jun-ya Kato, Edy Meiyanto
[ doi:10.21203/rs.3.rs-950137/v1 ]
"Curcumin Analogs, PGV-1 and CCA-1.1 Exhibit Anti-migratory Effects and Suppress MMP9 Expression on WiDr Cells," The Indonesian Biomedical Journal, vol.13, no.3, pp271-280, 9 Sep. 2021
Febri Wulandari, Mitsunori Kirihata, Jun-ya Kato, Edy Meiyanto
"Synthetic Inhibitors of CDK4/6 Activities and Tumor Suppression: A Preface to the Special Issue," Onco, vol.1, no.1, pp1-2, Sep. 2021
Chiaki Takahashi, Jun-ya Kato
"Curcumin-like structure (CCA-1.1) induces permanent mitotic arrest (Senescence) on Triple-negative breast cancer (TNBC) cells, 4T1," Research Journal of Pharmacy and Technology, vol.14, no.8, pp4375-4382, Aug. 2021
Dhania Novitasari, Riris Istighfari Jenie, Febri Wulandari, Rohmad Yudi Utomo, Dyaningtyas Dewi Pamungkas Putri, Jun-ya Kato, Edy Meiyanto
"Stabilization of fatty acid synthesis enzyme acetyl-CoA carboxylase 1 suppresses acute myeloid leukemia development," The Journal of clinical investigation, vol.131, no.12, 15 Jun. 2021
Hidenori Ito, Ikuko Nakamae, Jun-ya Kato, Noriko Yoneda-Kato
"CCA-1.1, a Novel Curcumin Analog, Exerts Cytotoxic anti-Migratory Activity toward TNBC and HER2-Enriched Breast Cancer Cells," Asian Pacific Journal of Cancer Prevention: APJCP, vol.22, no.6, pp1827, Jun. 2021
Dhania Novitasari, Riris Istighfari Jenie, Rohmad Yudi Utomo, Jun-ya Kato, Edy Meiyanto
"Evaluation of Cytotoxic Activity of Curcumin Like Structure (CCA-1.1) Against Metastatic Breast Cancer Cells," CANCER SCIENCE, vol.112, pp934, 1 Feb. 2021
Dhania Novitasari, Riris I Jenie, Dyaningtyas DD Putri, Febri Wulandari, Jun-ya Kato, Edy Meiyanto
"The Target Differences of Anti-Tumorigenesis Potential of Curcumin and Its Analogues Against HER-2 Positive and Triple-Negative Breast Cancer Cells.," Advanced Pharmaceutical Bulletin, 30 Sep. 2020
Meiyanto E,, Husnaa U,, Kastian RF,, Putri H,, Larasati YA,, Khumaira A,, Pamungkas DDP,, Jenie RI,, Kawaichi M,, Lestari B,, Yokoyama T,, Jun-ya Kato
[ doi:10.34172/apb.2021.020 ]
"New curcumin analog, CCA-1.1, synergistically improves the antiproliferative effect of doxorubicin against T47D breast cancer cells," Indonesian Journal of Pharmacy, pp244-256, Apr. 2020
F Wulandari, D Novitasari,, M Kirihata, Jun-ya Kato, E Meiyanto
"Curcumin derivatives verify the essentiality of ROS upregulation in tumor suppression," Molecules, vol.24(22), pp4067-4067, 10 Nov. 2019
Ikuko Nakamae, Tsumoru Morimoto, Hiroki Shima, Masafumi Shionyu, Hisayo Fujiki, Noriko Yoneda-Kato, Takashi Yokoyama, Shigehiko Kanaya, Kiyomi Kakiuchi, Tsuyoshi Shirai, Edy Meiyanto, Jun-ya Kato
[ doi:10.3390/molecules24224067 ]
"Pentagamavunon-1 (PGV-1) inhibits ROS metabolic ensymes and suppresses tumor cell growth by including M phase (prometaphase) arrest and cell senescence," Scientific Report, vol.9, pp14867-14867, 16 Oct. 2019
Beni Lestari, Ikuko Nakamae, Noriko Yoneda-Kato, Tsumoru Morimoto, Shigehiko Kanaya, Takashi Yokoyama, Masafumi Shionyu, Tsuyoshi Shirai, Edy Meiyant, Jun-ya Kato
[ doi:10.1038/s41598-019-51244-3 ]
"Pentagamavunon-1 (PGV-1) inhibits ROS metabolic enzymes and suppresses tumor cell growth by inducing M phase (prometaphase) arrest and cell senescence. ," Scientific Reports, 4 Oct. 2019
Beni Lestari,, Ikuko Nakamae, Noriko Yoneda-Kato,, Tsumoru Morimoto, Shigehiko Kanaya, Takashi Yokoyama, Masafumi Shionyu, Tsuyoshi Shirai,, Edy Meiyanto, Jun-ya Kato
[ NAISTレポジトリ ] [ doi:10.1038/s41598-019-51244-3 ]
"Anti-Proliferative and Anti-Metastatic Potential of Curcumin Analogue, Pentagamavunon-1 (Pgv-1), Toward Highly Metastatic Breast Cancer Cells in Correlation With Ros Generation. ," Advanced Pharmaceutical Bulletin, vol.9, no.3, pp445-452, 1 Sep. 2019
Meiyanto E, Putri H, Arum Larasati Y,, Yudi Utomo R, Jenie RI,, Ikawati M, Lestari B, Yoneda-Kato N, Nakamae I, Kawaichi M, Jun-ya Kato
"Cell cycle modulation of CHO-K1 cells under Genistein treatment correlates with cells senescence, apoptosis and ROS level but in a dose-dependent manner. ," Advanced Pharmaceutical Bulletin, vol.9, no.3, pp453-461, 1 Sep. 2019
Jenie RI,, Amalina ND, Ilmawati GPN, Utomo RY, Ikawati M, Jun-ya Kato, Meiyanto E
"Curcumin targets multiple enzymes involved in the ROS metabolic pathway to suppress tumor cell growth,," Scientific Reports, vol.8, pp2039, 1 Feb. 2018
Yonika Arum Larasati, Noriko Yoneda-Kato, Ikuko Nakamae, Takashi Yokoyama, Edy Meiyanto, Jun-ya Kato
[ NAISTレポジトリ ]
"Myeloid leukemia factor 1 stabilizes tumor suppressor C/EBPα to prevent Trib1-driven acute myeloid leukemia.," Blood Adv. , vol.1, no.20, pp1682-1693, 12 Sep. 2017
Nakamae I, Jun-ya Kato, Takashi Yokoyama, Ito H, Yoneda-Kato N
[ doi:10.1182/bloodadvances.2017007054. eCollection 2017 Sep 12. ]
"COP1 targets C/EBPα for degradation and induces acute myeloid leukemia via Trib1. ," Blood, vol.122, pp1750-1760, Sep. 2013
Yoshida A, Jun-ya Kato, Nakamae I, Noriko Kato
"The COP1 E3-ligase interacts with FIP200, a key regulator of mammalian autophagy.," BMC Biochem. , vol.14, no.1, 6 Jun. 2013
Kobayashi S, Noriko Kato, Itahara N, Yoshida A, Jun-ya Kato
[ doi:10.1186/1471-2091-14-1 ]
"CSN5 specifically interacts with CDK2 and controls senescence in a cytoplasmic cyclin E-mediated manner.," Sci Rep. 2013;. . Epub 2013 Jan 11. PMID: 23316279, no.3:1054, 11 Jan. 2013
Yoshida A, Noriko Kato, Jun-ya Kato
[ doi:10.1038/srep01054 ]
"Effects on Transcription of Mutations in ygjD, yeaZ, and yjeE Genes, Which Are Involved in a Universal tRNA Modification in Escherichia coli," J Bacteriol, vol.193, no.21, pp6075, Nov. 2011
Hashimoto, C, Sakaguchi, K, Taniguchi, Y, Honda, H, Oshima, T, Ogasawara, N, Kato, J.
"Overexpression of adenovirus-mediated p27kip1 lacking the Jab1-binding region enhances cytotoxicity and inhibits xenografted human cholangiocarcinoma growth.," Anticancer Res., vol.29, pp2015, 2009
Shiraso S, Katayose Y, Yamamoto K, Mizuma M, Yabuuchi S, Oda A, Rikiyama T, Onogawa T, Yoshida H, Hayashi H, Ohtsuka H, Motoi F, Egawa S, Kato J, Unno M.
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