学術論文 |
- "N-terminal truncation of PhaCBP-M-CPF4 and its effect on PHA production," Microbial Cell Factories, vol.23, no.1, pp52, 15 Feb. 2024
- Soon Zher Neoh, Hua Tiang Tan, Chanaporn Trakunjae, Min Fey Chek, Pilanee Vaithanomsat, Toshio Hakoshima, Kumar Sudesh
- "The SH3 binding site in front of the WH1 domain contributes to the membrane binding of the BAR domain protein endophilin A2," The Journal of Biochemistry, vol.175, no.1, pp57-67, 9 Oct. 2023
- Pei Fang Sim, Min Fey Chek, Nhung Thi Hong Nguyen, Tamako Nishimura, Takehiko Inaba, Toshio Hakoshima, Shiro Suetsugu
 [ doi:10.1093/jb/mvad065 ]
- "Characterization of the polyhydroxyalkanoate (PHA) synthase from Ideonella sakaiensis, a bacterium that is capable of degrading and assimilating poly (ethylene terephthalate)," Polymer Degradation and Stability, vol.206, pp110160, 1 Dec. 2022
- Hua Tiang Tan, Min Fey Chek, Soon Zher Neoh, Shaik Ling Ang, Shosuke Yoshida, Toshio Hakoshima, Kumar Sudesh
- "Crystal structure of a YeeE/YedE family protein engaged in thiosulfate uptake," SCIENCE ADVANCES, vol.6, ppeaba7637, 26 Aug. 2020
- Yoshiki Tanaka, Kunihito Yoshikaie, Azusa Takeuchi, Muneyoshi Ichikawa, Tomoyuki Mori, Sayaka Uchino, Yasunori Sugano, Toshio Hakoshima, Hiroshi Takagi, Gen Nonaka, Tomoya Tsukazaki
[ doi:10.1126/sciadv.aba7637 ]
- "Grip and slip of L1-CAM on adhesive substrates direct growth cone haptotaxis," Proc. Natl. Acad. Sci., 27 Feb. 2018
- Kouki Abe, Hiroko Katsuno, Michinori Toriyama, Kentarou Baba, Tomoyuki Mori, Toshio Hakoshima, Yonehiro Kanemura, Rikiya Watanabe, Naoyuki Inagaki
 [ NAISTレポジトリ ] [ doi:10.1073/pnas.1711667115 ]
- "Structural basis of thalidomide enantiomer binding to cereblon," Scientific Reports, vol.8, no.1294, 22 Jan. 2018
- Tomoyuki Mori, Takumi Ito, Shujie Liu, Hideki Ando, Satoshi Sakamoto, Yuki Yamaguchi, Etsuko Tokunaga, Norio Shibata, Hiroshi Handa, Toshio Hakoshima
[ doi:10.1038/s41598-018-19202-7 ]
- "Molecular Characterization of Viral Responsive Protein 15 and Its Possible Role in Nuclear Export of Virus in Black Tiger Shrimp Penaeus monodon," Scientific Reports, vol.7, no.1, pp6523, 26 Jul. 2017
- Jaturontakul K, Jatuyosporn T, Laohawutthichai P, Kim SY, Tomoyuki Mori, Supungul P, Toshio Hakoshima, Tassanakajon A, Krusong K
[ doi:10.1038/s41598-017-06653-7 ]
- "Structure of polyhydroxyalkanoate (PHA) synthase PhaC from Chromobacterium sp. USM2, producing biodegradable plastics.," Scientific Reports, vol.7, no.5312, 13 Jul. 2017
- Min Fey Chek, Sun-Yong Kim, Tomoyuki Mori, Hasni Arsad, Mohammed Razip Samian, Kumar Sudesh, Toshio Hakoshima
[ NAISTレポジトリ ] [ doi:10.1038/s41598-017-05509-4 ]
- "Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD," Nature Plants, vol.3, pp17010, 17 Feb. 2017
- Yoshinori Hirano, Masahiro Nakagawa, Tomoe Suyama, Kohji Murase, Maya Shirakawa, Seiji Takayama, Tai-ping Sun, Toshio Hakoshima
[ doi:10.1038/nplants.2017.10 ]
- "Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway," Scientific Reports, vol.6, pp28488, 23 Jun. 2016
- Kim SY, Tachioka Y, Mori T, Hakoshima T
[ NAISTレポジトリ ] [ doi:10.1038/srep28488 ]
- "Mechano-adaptive sensory mechanism of α-catenin under tension," Scientific Reports, vol.6, pp24878 , 25 Apr. 2016
- Maki K, Han SW, Hirano Y, Yonemura S, Hakoshima T, Adachi T
[ doi:10.1038/srep24878 ]
- "Efficient expression of SRK intracellular domain by a modeling-based protein engineering," Protein Expr Purif., vol.S1046-5928, no.15, pp30070-X, 18 Sep. 2015
- 村瀬 浩司, 平野 良憲, 高山 誠司, 箱嶋 敏雄
[ doi:10.1016/j.pep.2015.09.020 ]
- "MT1-MMP recognition by ERM proteins and its implication in CD44 shedding," Genes Cells., 20 Aug. 2015
- Terawaki SI, Ken Kitano, Aoyama M, Tomoyuki Mori, Toshio Hakoshima
[ doi:10.1111/gtc.12276 ]
- "Structure of the human DDB1–Cereblon–thalidomide complex," SPring-8 Research Frontiers 2014, pp28-29, Aug. 2015
- Tomoyuki Mori, Toshio Hakoshima
- "Structure of the free form of the N-terminal VH1 domain of monomeric α-catenin," FEBS Lett., vol.589, no.15, pp1754-1760, 8 Jul. 2015
- Shibahara T, Yoshinori Hirano, Toshio Hakoshima
[ doi:10.1016/j.febslet.2015.05.053 ]
- "知の扉を開く：タンパク質の複雑な構造から新たな機能を見いだす," 広報誌 「ならせんたん」 , vol.24, pp9-10, 2015.5
- 箱嶋 敏雄
- "Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs.," Nat Struct Mol Biol., vol.21, no.9, pp803-809, Sep. 2014
- Chamberlain PP, Lopez-Girona A, Miller K, Carmel G, Pagarigan B, Chie-Leon B, Rychak E, Corral LG, Ren YJ, Wang M, Riley M, Delker SL, Ito T, Ando H, Mori T, Hirano Y, Handa H, Hakoshima T, Daniel TO, Cathers BE
[ doi:10.1038/nsmb.2874 ]
- "Efficient and cost effective production of active-form human PKB using silkworm larvae," Sci Rep., vol.4, no.6016, 15 Aug. 2014
- Maesaki R, Satoh R, Taoka M, Kanaba T, Asano T, Fujita C, Fujiwara T, Ito Y, Isobe T, Toshio Hakoshima, Maenaka K, Mishima M
[ doi:10.1038/srep06016 ]
- "Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function," Genes Cells., vol.19, no.8, pp603-619, Aug. 2014
- Tomoyuki Mori, Gotoh S, Shirakawa M, Toshio Hakoshima
[ doi:10.1111/gtc.12161 ]
- "細胞内シグナル伝達," 日本の結晶学（Ⅱ）―輝かしき発展―, pp342-344, 2014.7
- 箱嶋 敏雄
- "シグナル伝達," 実験医学増刊 構造生命科学で何がわかるのか，何ができるのか, vol.32, no.10, pp187-192, 2014.6
- 箱嶋 敏雄
- "Mechanism of high-affinity abscisic acid binding to PYL9/RCAR1.," Genes Cells., vol.19, no.5, pp386-404, May. 2014
- Nakagawa M, Kagiyama M, Shibata N, Hirano Y, Hakoshima T.
[ doi:10.1111/gtc.12140 ]
- "Leucine Zippers," Citable Reviews in the Life Sciences (eLS 2014), 15 Apr. 2014
- Toshio Hakoshima
- "Structure of the RecQ C-terminal domain of human Bloom syndrome protein.," Scientific Report, vol.3, pp3294, 21 Nov. 2013
- Sun-Yong Kim, Toshio Hakoshima, Ken Kitano
[ NAISTレポジトリ ]
- "Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism," Proceedings of the National Academy of Sciences of the United States of America, vol.110, no.29, pp11821-11826, 1 Jul. 2013
- Ryou Nasuno, Yoshinori Hirano, Toshio Hakoshima, Hiroshi Takagi
[ doi:10.1073/pnas.1300558110 ]
- "Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism," Proceedings of the National Academy of Sciences of the United States of America, vol.110, no.29, pp11821-11826, Jul. 2013
- 那須野 亮, Yoshinori Hirano, Takafumi Itoh, 箱嶋 敏雄, Takao Hibi, 高木 博史
[ doi:10.1073/pnas.1300558110 ]
- "Microtubule-binding sites of the CH domain of EB1 and its autoinhibition revealed by NMR.," Biochimica et biophysica acta, vol.1834, no.2, pp499-507, 1 Feb. 2013
- Kanaba, T, Maesaki, R, Mori, T, Ito, Y, Hakoshima, T, Mishima, M
[ doi:10.1016/j.bbapap.2012.10.013 ]
- "Structures of D14 and D14L in the strigolactone and karrikin signaling pathways.," Genes Cells., vol.18, no.2, pp147, Feb. 2013
- Kagiyama M, Hirano Y, tomoyuki mori, Kim SY, Kyozuka J, Seto Y, Yamaguchi S, Hakoshima T.
- "Microtubule-binding sites of the CH domain of EB1 and its autoinhibition revealed by NMR.," Biochim Biophys Acta., vol.1834, no.2, pp499, Feb. 2013
- Kanaba T, Maesaki R, Tomoyuki Mori, Ito Y, Hakoshima T, Mishima M.
- "Structures of D14 and D14L in the strigolactone and karrikin signaling pathways.," Genes to cells, vol.18, no.2, pp147-160, 10 Jan. 2013
- Kagiyama, M, Hirano, Y, Mori, T, Kim, S. Y, Kyozuka, J, Seto, Y, Yamaguchi, S, Hakoshima, T
[ doi:10.1111/gtc.12025 ]
- "Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain," EMBO J., vol.30, no.13, pp2734-2747, Jun. 2011
- Hirano Y, Hatano T, Takahashi A, Toriyama M, Inagaki N, Hakoshima T.
[ doi:10.1038/emboj.2011.177 ]
- "Solution structure of the HRDC domain of human Bloom syndrome protein BLM.," J. Biochem., vol.148, no.4, pp517-525, Oct. 2010
- Akiko Sato, Masaki Mishima, Aki Nagai, Sun-Yong Kim, Yutaka Ito, Toshio Hakoshima, Jun-Goo Jee, Ken Kitano
- "Solution structure of the HRDC domain of human Bloom syndrome protein BLM.," J. Biochem., vol.148, no.4, pp517, Oct. 2010
- Akiko Sato, Masaki Mishima, Aki Nagai, Sun-Yong Kim, Yutaka Ito, Toshio Hakoshima, Jun-Goo Jee, Ken Kitano
[ doi:10.1093/jb/mvq097 ]
- "Solution structure of the HRDC domain of human Bloom syndrome protein BLM.," J. Biochem., vol.148, no.4, pp517, Oct. 2010
- Akiko Sato, Masaki Mishima, Aki Nagai, Sun-Yong Kim, Yutaka Ito, Toshio Hakoshima, Jun-Goo Jee, Ken Kitano
[ doi:10.1093/jb/mvq097 ]
- "Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule.," Proc. Natl. Acad. Sci. USA., vol.107, no.31, pp13666-13671, 3 Aug. 2010
- Akiyuki Nishimura, Ken Kitano, Jun Takasaki, Masatoshi Taniguchi, Norikazu Mizuno, Kenji Tago, Toshio Hakoshima, Hiroshi Itoh
- "Mechanism of hormone and effector recognition by the gibberellin receptor," SPring-8 Research Frontiers 2009, pp24-25, 2010.8
- 平野 良憲, 箱嶋 敏雄
- "Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule," Proc Natl Acad SciUSA, vol.107, no.31, pp13666-13671, Aug. 2010
- Nishimura A, Kitano K, Takasaki J, Taniguchi M, Mizuno N, Tago K, Hakoshima T, Itoh H.
[ doi:10.1073/pnas.1003553107 ]
- "Mechanism of hormone and effector recognition by the gibberellin receptor," SPring-8 Research Frontiers 2009, pp24, Aug. 2010
- Koji Murase, Yoshinori Hirano, Toshio Hakoshima
- "Mechanism of hormone and effector recognition by the gibberellin receptor," SPring-8 Research Frontiers 2009, pp24, Aug. 2010
- Koji Murase, Yoshinori Hirano, Toshio Hakoshima
- "Crystallization and preliminary X-ray crystallographic analysis of human phosphodiesterase 12," Acta Crystallogr. F, vol.65, no.5, pp520-522, 2010.5
- 香野哲也, Yamaguchi, H, 箱嶋 敏雄
- "Crystallization and preliminary X-ray crystallographic analysis of human phosphodiesterase 12.," Acta Crystallogr. F, vol.66, no.5, pp520, May. 2010
- Kohno, T, Yamaguchi, H., Hakoshima, T.
[ doi:10.1107/S1744309110008766 ]
- "Crystallization and preliminary X-ray crystallographic analysis of human phosphodiesterase 12.," Acta Crystallogr. F, vol.66, no.5, pp520, May. 2010
- Kohno, T, Yamaguchi, H., Hakoshima, T.
[ doi:10.1107/S1744309110008766 ]
- "Crystallization of the plant hormone receptors PYL9/RCAR1, PYL5/RCAR8 and PYR1/RCAR11 in the presence of (+)-abscisic acid.," Acta Crystallogr Sect F Struct Biol Cryst Commun., vol.66, pp456-459, 1 Apr. 2010
- Nobuyuki Shibata, Megumi Kagiyama, Masahiro Nakagawa, Yoshinori Hirano, Toshio Hakoshima
- "ジベレリンの受容と情報伝達の分子メカニズム," 植物の生長調節, vol.45, no.1, pp40-48, 2010.4
- 平野 良憲, 箱嶋 敏雄
- "ついに解明！！ジベレリンの作用機構-ジベレリンは「フタ」を閉じる," 化学, vol.65, no.4, pp30-35, 2010.4
- 村瀬浩司, 平野 良憲, 箱嶋 敏雄
- "Crystallization of the plant hormone receptors PYL9/RCAR1, PYL5/RCAR8, PYR1/RCAR11 in the presence of (+)-abscisic acid.," Acta Crystallogr. F, vol.66, no.4, pp456, Apr. 2010
- Shibata, N, Kagiyama, M, Nakagawa, M, Hirano, Y., Hakoshima, T.
[ doi:10.1107/S1744309110007037 ]
- "ジベレリンの受容と情報伝達の分子メカニズム．," 植物の生長調節, vol.45, no.1, pp40, 2010.4
- 村瀬浩司, Tai-ping Sun, 平野良憲, 箱嶋敏雄
- "ついに解明！！ジベレリンの作用機構-ジベレリンは「フタ」を閉じる," 化学, vol.65, no.4, pp30, 2010.4
- Koji Murase, Yoshinori Hirano, Toshio Hakoshima
- "Crystallization of the plant hormone receptors PYL9/RCAR1, PYL5/RCAR8, PYR1/RCAR11 in the presence of (+)-abscisic acid.," Acta Crystallogr. F, vol.66, no.4, pp456, Apr. 2010
- Shibata, N, Kagiyama, M, Nakagawa, M, Hirano, Y., Hakoshima, T.
[ doi:10.1107/S1744309110007037 ]
- "Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN," Structure, vol.18, no.2, pp177-187, 10 Feb. 2010
- Ken Kitano, Sun-Yong Kim, Toshio Hakoshima
- "ジベレリン受容体のジベレリン識別とエフェクター認識," 日本結晶学会誌, vol.52, no.1, pp37, 2010.2
- 箱嶋敏雄, 村瀬浩司, 平野良憲, Tai-ping Sun
- "ジベレリン受容体のジベレリン識別とエフェクター認識," 日本結晶学会誌, vol.52, no.1, pp37, 2010.2
- 箱嶋敏雄, 村瀬浩司, 平野良憲, Tai-ping Sun
- "The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module.," EMBO J., vol.29, no.1, pp236-250, Jan. 2010
- Shin-ichi Terawaki, Ken Kitano, Tomoyuki Mori, Yan Zhai, Yoshiki Higuchi, Norimichi Itoh, Takashi Watanabe, Kozo Kaibuchi, Toshio Hakoshima
- "2009年ノーベル賞を読み解く：リボソームの構造と機能の研究," 化学, vol.65, no.1, pp45, 2010.1
- 森智行, 箱嶋敏雄
- "The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module.," EMBO J, vol.29, no.1, pp236-250, 2010.1
- Terawaki, S, Kitano, K, Mori, T, Zhai, Y, Higuchi, Y, Itoh, N, Watanabe, T, Kaibuchi, K, Hakoshima, T
[ doi:10.1038/emboj.2009.323 ]
- "2009年ノーベル賞を読み解く：リボソームの構造と機能の研究," 化学, vol.65, no.1, pp45, 2010.1
- 森智行, 箱嶋敏雄
- "植物によるジベレリンの感知とシグナル伝達," 生物物理, vol.49, no.4, pp200-201, 2009.7.25
- 箱嶋 敏雄, 平野 良憲, 村瀬 浩司, Tai-ping Sun
- "植物によるジベレリンの感知とシグナル伝達," 生物物理, vol.49, no.4, pp200, 2009.7
- 箱嶋敏雄, 平野良憲, 村瀬浩司, Tai-ping Sun
- "植物によるジベレリンの感知とシグナル伝達," 生物物理, vol.49, no.4, pp200, 2009.7
- 箱嶋敏雄, 平野良憲, 村瀬浩司, Tai-ping Sun
- "植物ホルモン受容体によるシグナル伝達制御の構造研究," 蛋白質核酸酵素, vol.54, no.7, pp833-842, 2009.6.1
- 平野 良憲, 村瀬 浩司, 箱嶋 敏雄
- "植物ホルモン受容体によるシグナル伝達制御の構造研究," 蛋白質核酸酵素, vol.54, no.7, pp833, 2009.5
- 平野良憲, 村瀬浩司, 箱嶋敏雄
- "植物ホルモン受容体によるシグナル伝達制御の構造研究," 蛋白質核酸酵素, vol.54, no.7, pp833, 2009.5
- 平野良憲, 村瀬浩司, 箱嶋敏雄
- "ジベレリン受容体の構造と機能の解明：植物ホルモン識別と標的タンパク質認識の機構," 細胞工学, vol.28, no.2, pp162-163, 2009.1.22
- 箱嶋 敏雄, 村瀬 浩司, 平野 良憲
- "Gibberellin-induced DELLA recognition by the gibberellin receptor GID1.," Nature, vol.456, no.7221, pp459-464, 27 Nov. 2008
- Kohji Murase, Yoshinori Hirano, Tai-pin Sun, Toshio Hakoshima
- "A molecular mechanism of P-loop pliability of Rho-kinase investigated by molecular dynamic simulation.," J. Comput. Aided Mol. Des., vol.22, no.11, pp789-797, Nov. 2008
- Keigo Gohda, Toshio Hakoshima
- "Crystallographic characterization of the membrane-targeting domain of Rac-specific guanine nucleotide exchange factors Tiam1 and 2.," Acta Crystallogr. F, vol.F64, no.11, pp1039-1042, Nov. 2008
- Shin-ichi Terawaki, Ken Kitano, Toshio Hakoshima
- "Crystallographic characterization of the membrane-targeting domain of Rac-specific guanine nucleotide exchange factors Tiam1 and 2.," Acta Cryst. F, vol.64, no.11, pp1039, Nov. 2008
- Shin-ichi Terawaki, Ken Kitano, Toshio Hakoshima
[ doi:10.1107/S1744309108031692 ]
- "Gibberellin-induced DELLA recognition by the gibberellin receptor GID1.," Nature, vol.456, no.7221, pp459, Nov. 2008
- Koji Murase, Yoshinori Hirano, Tai-ping Sun, Toshio Hakoshima
[ doi:10.1038/nature07519 ]
- "Crystallographic characterization of the membrane-targeting domain of Rac-specific guanine nucleotide exchange factors Tiam1 and 2.," Acta Cryst. F, vol.64, no.11, pp1039, Nov. 2008
- Shin-ichi Terawaki, Ken Kitano, Toshio Hakoshima
[ doi:10.1107/S1744309108031692 ]
- "Structural Basis for CD44 Recognition by ERM Proteins," J. Biol. Chem., vol.283, no.43, pp29602-29612, 24 Oct. 2008
- Tomoyuki Mori, Ken Kitano, Shin-ichi Terawaki, Ryoko Maesaki, Yayoi Fukami, Toshio Hakoshima
- "Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of membrane-type 1 matrix metalloproteinase (MT1-MMP)," Acta Crystallogr. F, vol.64, no.1, pp39-43, Oct. 2008
- Shin-ichi Terawaki, Ken Kitano, Miki Aoyama, Toshio Hakoshima
- "Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of membrane-type 1 matrix metalloproteinase (MT1-MMP)," Acta Cryst. F, vol.64, no.10, pp911, Oct. 2008
- Shin-ichi Terawaki, Ken Kitano, Miki Aoyama, Toshio Hakoshima
[ doi:10.1107/S1744309108026869 ]
- "Structural basis for CD44 recognition by ERM proteins.," J. Biol. Chem., vol.283, no.43, pp29602, Oct. 2008
- Tomoyuki Mori, Ken Kitano, Shin-ichi Terawaki, Ryoko Maesaki, Yayoi Fukami, Toshio Hakoshima
[ doi:10.1074/jbc.M803606200 ]
- "Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of membrane-type 1 matrix metalloproteinase (MT1-MMP)," Acta Cryst. F, vol.64, no.10, pp911, Oct. 2008
- Shin-ichi Terawaki, Ken Kitano, Miki Aoyama, Toshio Hakoshima
[ doi:10.1107/S1744309108026869 ]
- "Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins.," J. Mol. Biol., vol.381, no.3, pp634-644, 5 Sep. 2008
- Yumiko Takai, Ken Kitano, Shin-ichi Terawaki, Ryoko Maesaki, Toshio Hakoshima
- "Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins.," J. Mol. Biol., vol.381, no.3, pp634, Sep. 2008
- YumikoTakai, Ken Kitano, Shin-ichi Terawaki, Ryoko Maesaki, Toshio Hakoshima
[ doi:10.1016/j.jmb.2008.05.085 ]
- "Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins.," J. Mol. Biol., vol.381, no.3, pp634, Sep. 2008
- YumikoTakai, Ken Kitano, Shin-ichi Terawaki, Ryoko Maesaki, Toshio Hakoshima
[ doi:10.1016/j.jmb.2008.05.085 ]
- "Structural basis for CD44 recognition by ERM proteins.," J Biol Chem. , vol.283, no.43, pp29602-12-29612, Aug. 2008
- Mori, T, Kitano, K, Terawaki, S, Maesaki, R, Fukami, Y, Hakoshima, T
- "Crystallization and preliminary crystallographic analysis of the catalytic domain of human flap endonuclease-1 FEN1 in complex with a nicked DNA product: Use of a DPCS kit for efficient protein-DNA complex crystallization.," Acta Crystallogr. F, vol.64, no.1, pp39-43, Jan. 2008
- Shigeru Sakurai, Ken Kitano, Hiroshi Morioka, Toshio Hakoshima
- "微小管ダイナミクスを制御する蛋白質の構造研究," 蛋白質核酸酵素, vol.53, no.2, pp139-147, 2008.1
- 前崎 綾子, 三島 正規, 箱嶋 敏雄
- "血管収縮阻害剤：Rhoキナーゼの構造と機能," 医薬ジャーナル 連載「分子構造から考える薬物の作用機序(12)」, vol.44, no.1, pp5-10, 2008.1
- 合田 圭吾, 箱嶋 敏雄
- "Structural basis of PSGL-1 binding to ERM proteins. ," Genes to Cells, vol.12, no.12, pp1329-1338, Dec. 2007
- Yumiko Takai, Ken Kitano, Shin-ichi Terawaki, Ryoko Maesaki, Toshio Hakoshima
- "Crystallization and preliminary crystallographic analysis of the catalytic domain of human flap endonuclease 1 in complex with a nicked DNA product: use of a DPCS kit for efficient protein-DNA complex crystallization.," Acta Crystallogr Sect F Struct Biol Cryst Commun, vol.64, pp39, Dec. 2007
- Sakurai, S, Kitano, K, Morioka, H, Hakoshima, T.
[ doi:10.1107/s1744309107065372 ]
- "Structural basis of PSGL-1 binding to ERM proteins.," Genes Cells, vol.12, pp1329, Dec. 2007
- Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T.
[ doi:10.1111/j.1365-2443.2007.01137.x ]
- "Crystallization and preliminary crystallographic analysis of the catalytic domain of human flap endonuclease 1 in complex with a nicked DNA product: use of a DPCS kit for efficient protein-DNA complex crystallization.," Acta Crystallogr Sect F Struct Biol Cryst Commun, vol.64, pp39, Dec. 2007
- Sakurai, S, Kitano, K, Morioka, H, Hakoshima, T.
[ doi:10.1107/s1744309107065372 ]
- "P-loop pliability of Rho-kinase for inhibitor binding.," Drug Design Research Perspectives , pp39-55, Dec. 2007
- Keigo Gohda, Toshio Hakoshima
- "Crystallographic characterization of the radixinFERM domain bound to the cytoplasmic tail of adhesion molecule CD44.," Acta Crystallogr. F, vol.63, no.10, pp844-847, Oct. 2007
- Tomoyuki Mori, Ken Kitano, Shin-ichi Terawaki, Ryoko Maesaki, Toshio Hakoshima
- "Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of adhesion molecule CD44.," Acta Crystallogr Sect F Struct Biol Cryst Commun, vol.63, pp844, Oct. 2007
- Mori, T, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T.
[ doi:10.1107/s1744309107041152 ]
- "Structure of SixA, a histidine protein phosphatase of the ArcB HPt domain in E. coli.," Methods in Enzymology , vol.422, pp288-304, 10 Jul. 2007
- Toshio Hakoshima, Hisako Ichihara
- "Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex.," J. Biol. Chem., vol.282, no.27, pp19854-19862, 6 Jul. 2007
- Shin-ichi Terawaki, Ken Kitano, Toshio Hakoshima
- "Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex.," J Biol Chem, vol.282, pp19854, Jul. 2007
- Terawaki, S. I, Kitano, K., Hakoshima, T.
[ doi:10.1074/jbc.M609232200 ]
- "Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex.," J Biol Chem, vol.282, pp19854, Jul. 2007
- Terawaki, S. I, Kitano, K., Hakoshima, T.
[ doi:10.1074/jbc.M609232200 ]
- "Structural basis for the CLIP-170 CAP-Gly domain grasping the C-terminal acidic tail of alpha-tubulin. ," Proc. Natl. Acad. Sci. USA., vol.104, no.25, pp10346-10351, 19 Jun. 2007
- Masaki Mishima, Ryoko Maesaki, Miyuki Kasa, Takashi Watanabe, Masaki Fukata, Kozo Kaibuchi, Toshio Hakoshima
- "Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition.," Proc Natl Acad Sci USA, vol.104, pp10346, Jun. 2007
- Mishima, M, Maesaki, R, Kasa, M, Watanabe, T, Fukata, M, Kaibuchi, K., Hakoshima, T.
[ doi:10.1073/pnas.0703876104 ]
- "Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition.," Proc Natl Acad Sci USA, vol.104, pp10346, Jun. 2007
- Mishima, M, Maesaki, R, Kasa, M, Watanabe, T, Fukata, M, Kaibuchi, K., Hakoshima, T.
[ doi:10.1073/pnas.0703876104 ]
- "Crystal structure of the HRDC domain of human Werner syndrome protein, WRN.," J. Biol. Chem., vol.282, no.4, pp2717-2728, 26 Jan. 2007
- Ken Kitano, Nozomi Yoshihara, Toshio Hakoshima
- "Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tails of adhesion molecules CD43 and PSGL-1.," Acta Crystallogr., F, vol.63, no.1, pp49-51, Jan. 2007
- Yumiko Takai, Ken Kitano, Shin-ichi Terawaki, Ryoko Maesaki, Toshio Hakoshima
- "A diphtheria toxin receptor deficient in epidermal growth factor-like biological activity. ," J. Biochem., vol.140, no.6, pp831-841, Dec. 2006
- Norihisa Furukawa, Michiko Saito, Toshio Hakoshima, Kenji Khono
- "Crystal structure of human flap endonuclease-1 (FEN1) complexed to PCNA," SPring-8 Research Frontiers, pp18-19, Nov. 2006
- Ken Kitano, Shigeru Sakurai, Toshio Hakoshima
- "ヒトFEN1-PCNA複合体の結晶構造が示すスイング活性化機構," 日本結晶学会誌, vol.48, no.10, ppin press, 2006.10
- 北野 健, 箱嶋 敏雄
- "Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y27632," J. Biochem., vol.140, no.3, pp305-311, Sep. 2006
- Hiroto Yamaguchi, Yukiko Miwa, Miyuki Kasa, Ken Kitano, Mutsuki Amano, Kozo Kaibuchi, Toshio Hakoshima
- "Crystal structure of human Rad GTPase of the RGK-family.," Genes Cells, vol.11, no.8, pp961-968, Aug. 2006
- Arry Yanuar, Shigeru Sakurai, Ken Kitano, Toshio Hakoshima
- "蛋白質キナーゼの構造生物学-RhoキナーゼおよびAGCキナーゼ群における最近の進歩," 蛋白質核酸酵素, vol.51, no.11, pp1557-1568, 2006.8
- 箱嶋 敏雄
- "Rhoキナーゼの触媒ドメインにみられる新規な構造的活性制御," 細胞工学, vol.25, no.5, pp512-513, 2006.5
- 山口 寛人, 箱嶋 敏雄
- "Structural Basis for NHERF Recognition by ERM Proteins.," Structure, vol.14, no.4, pp777-789, Apr. 2006
- Shin-ichi Terawaki, Ryoko Maesaki, Toshio Hakoshima
- "Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295–304.," Acta Crystallogr. F, vol.F62, no.4, pp340-345, Apr. 2006
- Ken Kitano, Fumie Yusa, Toshio Hakoshima
- "Molecular mechanism for the regulation of Rho-kinase by dimerization and its inhibition by fasudil," Structure, vol.14, no.3, pp589-600, Mar. 2006
- Hiroto Yamaguchi, Miyuki Kasa, Mutsuki Amano, Kozo Kaibuchi, Toshio Hakoshima
- "Expression, purification, crystallization and preliminarycrystallographic analysis of human Rad GTPase," Acta Crystallogr. F, vol.61, no.11, pp978-980, Nov. 2005
- Arry Yanuar, Shigeru Sakurai, Ken Kitano, Toshio Hakoshima
- "Crystal structure of decameric peroxiredoxin (AhpC) from Amphibacillusxylanus.," Proteins, vol.59, no.3, pp644-647, May. 2005
- Ken Kitano, Akiko Kita, Toshio Hakoshima, Youichi Niimura, Kunio Miki
- "Structural basis for recruitment of human flap endonuclease 1 to PCNA.," EMBO J., vol.24, no.4, pp683-693, Apr. 2005
- Shigeru Sakurai, Ken Kitano, Hiroto Yamaguchi, Kengo Okada, Keisuke Hamada, Kotaro Fukuda, Makiyo Uchida, Eiko Ohtsuka, Hiroshi Morioka, Toshio Hakoshima
- "Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay.," Genes to Cells, vol.10, no.1, pp1-11, Jan. 2005
- Keisuke Hamada, Masato Kato, Toshiyuki Shimizu, Kentaro Ihara, Takeshi Mizuno, Toshio Hakoshima
- "Structural basis of biopterin-induced inhibition of GTP cyclohydrolaseI by GFRP, its feedback regulatory proteins.," J. Biol. Chem., vol.279, no.49, pp51534-51540, Dec. 2004
- Nobuo Maita, Kengo Okada, Kazuyuki Hatakeyama, Toshio Hakoshima
- "核酸分子認識とその機能を中心とした構造生物学," 日本結晶学会誌, vol.46, pp201-208, 2004.6
- 箱嶋 敏雄
- "Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase. ," J. Biol. Chem., vol.278, no.46, pp46046-46051, Nov. 2003
- Toshiyuki Shimizu, Kentaro Ihara, Ryoko Maesaki, Mutsuki Amano, Kozo Kaibuchi, Toshio Hakoshima
- "Leucine zippers.," Nature Encyclopedia of the Human Genome, vol.vol.3, pp679-683, Oct. 2003
- Toshio Hakoshima
- "Structural basis of the Rho GTPase signaling.," J. Biochem. (Tokyo) , vol.134, no.3, pp327-331, Sep. 2003
- Toshio Hakoshima, Toshiyuki Shimizu, Ryoko Maesaki
- "Preparation and crystallization of human flap endonuclease FEN-1 in complex with proliferating-cell nuclear antigen, PCNA.," Acta Crystallogr. D, vol.59, no.5, pp933-935, May. 2003
- Shigeru Sakurai, Ken Kitano, Kengo Okada, Keisuke Hamada, Hiroshi Morioka, Toshio Hakoshima
- "Structural basis of adhesion protein recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex.," EMBO J., vol.22, no.3, pp502-514, Feb. 2003
- Keisuke Hamada, Toshiyuki Shimizu, Shigenobu Yonemura, Shoichiro Tsukita, Sachiko Tsukita, Toshio Hakoshima
- "Crystallographic characterization of the radixin FERM domain bound to the C-terminal region of the human Na+/H+ exchanger regulatory factor (NHERF).," Acta Crystallogr., vol.D59, no.1, pp177-179, Jan. 2003
- Shin-ichi Terawaki, Ryoko Maesaki, Kengo Okada, Toshio Hakoshima
- "Rhoシグナリングの構造生物学," 生化学「特集：構造生物学の最前線」（稲垣冬彦・箱嶋敏雄編）日本生化学会, vol.74, no.10, pp1237-1242, 2002.10
- 箱嶋敏雄
- "The crystal structure of N1-[2-(2-amino-ethylamino)-ethyl]-ethane-1,2-diamine (polyamines) binding to the minor groove of d(CGCGCG)2, hexamer at room temperature. ," FEBS Lett., vol.523, no.1-3, pp29-34, Jul. 2002
- Ohishi H., Suzuki K., Ohtsuchi M., Hakoshima T., Rich A.
- "Role of loop structures of neuropsin in the activity of serine protease and regulated secretion," J. Biol. Chem., vol.277, no.17, pp14724-14730, Apr. 2002
- Oka T., Hakoshima T., Itakura M., Yamamori S., Takahashi M., Hashimoto Y., Shiosaka S., Kato K.
- "Structural basis for neurofibromatosis Type 2: Crystal structure of the Merlin FERM domain.," J. Biol. Chem., vol.277, no.12, pp10332-10336, Mar. 2002
- Toshiyuki Shimizu, Azusa Seto, Nobuo Maita, Keisuke Hamada, Shoichiro Tsukita, Sachiko Tsukita, Toshio Hakoshima
- "Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP. ," Proc. Natl. Acad. Sci. USA , vol.99, no.3, pp12121-1217, Feb. 2002
- Nobuo Maita, Kengo Okada, Kazuyuki Hatakeyama, Toshio Hakoshima
- "接着分子-受容体に集積する蛋白質の構造研究、「特集：大きな構造フレームで捉えるシグナル伝達」," 蛋白質核酸酵素, vol.46, no.13, pp1929-1935, 2001.10
- 浜田 恵輔, 箱嶋 敏雄
- "総論：シグナル伝達の構造フレームを考える：細胞外マトリックス・受容体/細胞接着分子・細胞骨格を考える、「特集：大きな構造フレームで捉えるシグナル伝達」," 蛋白質核酸酵素, vol.46, no.13, pp1915-1921, 2001.10
- 箱嶋 敏雄
- "Amadori転移を利用する酵素GTP cyclohydrolase I の反応機構," 化学, vol.56, no.10, pp62-63, 2001.10
- 箱嶋 敏雄, 真板 宣夫
- "Preparation and crystallization of the stimulatory and inhibitory complexes of GTP cyclohydrase I and its feedback regulatory protein GFRP.," Acta Crystallogr. D, vol.57, no.8, pp1153-1156, Aug. 2001
- Nobuo Maita, Kengo Okada, Shoko Hirotsu, Kazuyuki Hatakeyama, Toshio Hakoshima
- "転写因子によるDNA認識の多様性," 蛋白質核酸酵素8月号増刊号「新世紀における蛋白質科学の進展」, pp1602-1607, 2001.8
- 清水 敏之, 箱嶋 敏雄
- "Structural conversion between open and closed forms of radixin: low-angle shadowing electron microscopy.," J. Mol. Biol. , vol.310, no.5, pp973-978, Jul. 2001
- H. Ishikawa, A. Tamura, T. Matsui, H. Sasaki, Toshio Hakoshima, Shoichiro Tsukita, Sachiko Tsukita
- "Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of the adhesion protein ICAM-2.," Acta Crystallogr. D, vol.57, no.6, pp891-892, Jun. 2001
- Keisuke Hamada, Toshiyuki Shimizu, T. Matsui, Shoichiro Tsukita, Sachiko Tsukita, Toshio Hakoshima
- "Crystallization and preliminary crystallographic studies RhoGDI in complex with the radixin FERM domain.," Acta Crystallogr. D, vol.57, no.6, pp889-890, Jun. 2001
- Keisuke Hamada, Azusa Seto, Toshiyuki Shimizu, T. Matsui, Y. Takai, Shoichiro Tsukita, Sachiko Tsukita, Toshio Hakoshima
- "細胞骨格を膜に連結するERM蛋白質と細胞膜・接着分子との相互作用：ラディキシンのFERMドメインの結晶構造研究," 生物物理, vol.41, no.5, pp230-234, 2001.5
- 浜田 恵輔, 箱嶋 敏雄
- "GTP cyclohydrolase I / GFRP複合体の結晶構造解析," 構造生物, vol.7, no.3, pp19-26, 2001
- 真板 宣夫, 岡田 健吾, 畠山 和幸, 箱嶋 敏雄
- "Structural basis for the diversity of DNA recognition by bZIP transcription factors.," Nature Struct. Biol., vol.7, no.10, pp889-893, Oct. 2000
- Yoshifumi Fujii, Toshiyuki Shimizu, T. Toda, M. Yanagida, Toshio Hakoshima
- "低分子量Ｇタンパク質Rhoによる分子認識機構," 日本結晶学会誌, vol.42, no.5, pp435-442, 2000.10
- 前崎 綾子, 箱嶋 敏雄
- "Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.," EMBO J. , vol.19, no.17, pp4449-4462, 1 Sep. 2000
- Keisuke Hamada, Toshiyuki Shimizu, T. Matsui, Shoichiro Tsukita, Sachiko Tsukita, Toshio Hakoshima
- "Crystallographic characterization of the membrane-binding domain of radixin.," Acta Crystallogr. D, vol.56, no.7, pp922-923, Jul. 2000
- Keisuke Hamada, T. Matsui, Shoichiro Tsukita, Sachiko Tsukita, Toshio Hakoshima
- "An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RhoA complexed with GDP: Implication for the GDP/DTP exchange mechanism.," J. Biol. Chem., vol.275, no.24, pp18311-18317, 16 Jun. 2000
- Toshiyuki Shimizu, Kentaro Ihara, Ryoko Maesaki, S. Kuroda, Kozo Kaibuchi, Toshio Hakoshima
- "Z-DNAの復権：左巻きZ-DNA結合蛋白質複合体の構造解析とその生物学的意義," 蛋白質核酸酵素, vol.45, no.4, pp595-599, 2000.4
- 箱嶋 敏雄
- "マルチドメイン蛋白質複合体のＸ線結晶構造解析," 実験医学増刊号（竹縄忠臣編）「次世代のシグナル蛋白質研究：プロテオーム研究とシグナル蛋白ドメイン」, vol.18, no.18, pp65-71, 2000
- 箱嶋 敏雄
- "ヘリックス-ループ-ヘリックス（HLH）蛋白質の構造的基盤," 実験医学増刊号（竹縄忠臣編）「次世代のシグナル蛋白質研究：プロテオーム研究とシグナル蛋白ドメイン」, vol.18, no.18, pp164-170, 2000
- 清水 敏之, 箱嶋 敏雄
- "ペルオキシレドキシンの分子機能の構造的基礎、," 蛋白質核酸酵素, vol.45, no.15, pp2463-2474, 2000
- 広津 晶子, 阿部 靖子, 西野 武士, 箱嶋 敏雄
- "蛋白質のDNAシグナル認識の構造研究," 蛋白質核酸酵素増刊号(石井他編)、「転写因子の機能—転写制御複合体形成のダイナミックス」, vol.45, no.9, pp1671-1672, 2000
- 清水 敏之, 箱嶋 敏雄
- "The structural basis of Rho effector recognition revealed by the Crystal structure of human RhoA complexed with the effector domain of PKN/PRK1.," Molecular Cell , vol.4, no.5, pp799-803, Nov. 1999
- Ryoko Maesaki, Kentaro Ihara, Toshiyuki Shimizu, S. Kuroda, Kozo Kaibuchi, Toshio Hakoshima
- "Refined structure of the histidine-containing phosphotransfer (HPt) domain of the anaerobic sensor kinase ArcB from Escherichia coli at 1.57 Å resolution. ," Acta Crystallogr. D, vol.55, no.11, pp1842-1849, Nov. 1999
- Masato Kato, Takeshi Mizuno, Toshiyuki Shimizu, Toshio Hakoshima
- "Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa / proliferation-associated gene product.," Proc. Natl. Acad. Sci. USA , vol.96, no.22, pp12333-12338, 26 Oct. 1999
- Shoko Hirotsu, Y. Abe, Kengo Okada, N. Nagahara, H. Hori, T. Nishio, Toshio Hakoshima
- "Crystal structure of an IRF/DNA complex reveals novel DNA recognition and cooperactive binding to a tandem repeat of the core sequences.," EMBO J., vol.18, no.18, pp5028-5041, 15 Sep. 1999
- Yoshifumi Fujii, Toshiyuki Shimizu, M. Kusumoto, Y. Kyogoku, T. Taniguchi, Toshio Hakoshima
- "N-Glycan structures of murine hippocampus serine protease, neuropsin, produced in Trichoplusia ni cells.," Glycoconjugate J., vol.16, no.8, pp405-414, Aug. 1999
- N. Takahashi, Y. Tsukamoto, S. Shiosaka, Toshio Hakoshima, Y. Arata, K. Kato, I. Shimada
- "Structure of the histidine containing phosphotransfer (HPt) domain of the anaerobic sensor kinase ArcB complexed with the chemotaxis response regulator CheY.," Acta Crystallogr. D, vol.55, no.7, pp1257-1263, Jul. 1999
- Masato Kato, Takeshi Mizuno, Toshiyuki Shimizu, Toshio Hakoshima
- "Biochemical and crystallographic characterization of a Rho effector domain of the protein serine/threonine kinase N in a complex with RhoA. ," J. Struct. Biol., vol.126, no.2, pp166-170, 15 Jun. 1999
- Ryoko Maesaki, Toshiyuki Shimizu, Kentaro Ihara, S. Kuroda, Kozo Kaibuchi, Toshio Hakoshima
- "Crystallographic characterization of a stress-induced multifunctional protein, rat HBP-23.," J. Struct. Biol., vol.126, no.1, pp80-83, 1 Jun. 1999
- Shoko Hirotsu, Y. Abe, N. Nagahara, H. Hori, T. Nishino, Kengo Okada, Toshio Hakoshima
- "Crystal structure of neuropsin, a hippocampal protease involved in kindling epileptogenesis. ," J. Biol. Chem., vol.274, no.7, pp4220-4224, 12 Feb. 1999
- Tadaaki Kishi, Masato Kato, Toshiyuki Shimizu, K. Kato, K. Matsumoto, S. Yoshida, S. Shiosaka, Toshio Hakoshima
- "Crystallographic characterization of a novel protein SixA which exhibits phospho-histidine phosphatase activity in the multistep His-Asp phosphorelay.," Acta Crystallogr. D, vol.55, no.1, pp269-271, Jan. 1999
- Keisuke Hamada, Masato Kato, Takeshi Mizuno, Toshio Hakoshima
- "Interaction between the left handed Z-DNA and polyamine -3: Crystal structure of a left-handed Z-DNA hexamer, d(CG)3, duplex complexed with synthetic polyamine reveals binding of a polyamine in the minor groove. ," Nucleosides & Nucleotides, vol.18, no.6&7, pp1567-1569, 1999
- K. Tomita, H. Ohishi, I. Nakanishi, Toshio Hakoshima, A. Rich
- "サイトカインレセプター下の細胞内情報伝達：三次元構造解析によるアプローチ," 細胞工学、「構造生物学が解明するシグナル伝達：三次元構造から機能を探る」, vol.18, no.10, pp1474-1480, 1999
- 清水 敏之, 藤井 佳史, 箱嶋 敏雄
- "低分子量Ｇタンパク質はエフェクターの数だけ認識様式を持つ," 細胞工学、「構造生物学が解明するシグナル伝達：三次元構造から機能を探る」, vol.18, no.10, pp1459-1466, 1999
- 前崎 綾子, 伊原 健太郎, 箱嶋 敏雄
- "細胞内ネットワークを解く構造生物学," 細胞工学、「構造生物学が解明するシグナル伝達：三次元構造から機能を探る」, vol.18, no.10, pp1453-1457, 1999
- 箱嶋 敏雄
- "リン酸化と脱リン酸化によるシグナル伝達、," 第13回大学と科学公開シンポジウム「遺伝子産物（タンパク質）の形を観る」, pp112-121, 1999
- 箱嶋 敏雄
- "低分子量Ｇタンパク質の構造生物学," 蛋白質核酸酵素増刊号、「構造生物学のフロンティア」, vol.44, no.4, pp380-394, 1999
- 伊原 健太郎, 箱嶋 敏雄
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