研究キーワード
脂質ドメイン, 抗菌性高分子, リポソーム, 脂質2分子膜
研究分野
ライフサイエンス / 生物物理学 / , ナノテク・材料 / 生体化学 / , ナノテク・材料 / 機能物性化学 / , ナノテク・材料 / 高分子化学 / , ナノテク・材料 / 基礎物理化学 /
研究室概要
バイオミメティックスおよびテクノミメティクスに基づく分子マシンの設計 ・ 合成とナノ機械工学および生物応用に関する研究・教育を行う。
学術論文
"Cascade Fluorescence Modulation in Photochromic Microcapsules," ACS Applied Materials & Interface, 25 Sep. 2024
Magin Benedict Ferrer, Daiyu Harada, Colin J. Martin, Rémi Métivier, Clémence Allain, Keitaro Nakatani, Marine Louis, Noriaki Kawaguchi, Takayuki Yanagida, Kazuma Yasuhara, Tsuyoshi Kawai
[ doi:10.1021/acsami.4c09023 ]
"Synthesis of Ce(IV) Heteroleptic Double-Decker Complex with a New Helical Naphthalocyanine as a Potential Gearing Subunit," Chem. Eur. J. , vol.30, 29 Jul. 2024
J. D. Subramanian, Hattori Yohei, F. Asanoma, T. Nishino, K. Yasuhara, C. J. Martin, Gwenael Rapenne
[ doi:10.1002/chem.202402470 ]
"Procrystalline self-assembly of desymmetrized pentaphenylcyclopentadiene," J. Phys. Chem. Lett. , vol.15, pp7628-7634, 20 Jul. 2024
D. Li, S. Seki, A. Ishikawa, K. Omoto, K. Yasuhara, G. Rapenne, S. Kawai
[ doi:10.1021/acs.jpclett.4c01364 ]
"Lipid nanodiscs spontaneously formed by an amphiphilic polymethacrylate derivative as an efficient nanocarrier for molecular delivery to intact cells ," RSC Advances , vol.14, pp6127-6134, 19 Feb. 2024
J. Hao, G. Rapenne, K. Yasuhara
[ doi:10.1039/D3RA07481A ]
"Synthesis and dynamic behavior of Ce(IV) double-decker complexes of sterically-hindered phthalocyanines," Molecules , vol.29, pp888, 17 Feb. 2024
J. D. Subramanian, T. Nishino, K. Yasuhara, G. Rapenne
[ doi:10.3390/molecules29040888 ]
"Curcumin Modulates the Membrane Raft Integrity via Phase Separation and Induces CD44 Shedding in Tumor Cells T. Murai, Y. Masaki, K. Yasuhara," Biochemistry , vol.63, pp441-445, 22 Jan. 2024
T. Murai, Y. Masaki, K. Yasuhara
[ doi:10.1021/acs.biochem.3c00645 ]
"Lipid cubic phase with an organic-inorganic hybrid structure formed by organoalkoxysilane lipid," Chem. Commun. , vol.60, pp2168-2171, 11 Jan. 2024
M. Kariya, K. Omoto, K. Nomura, K. Yonezawa, H. Kamikubo, T. Nishino, T. Inoie, G. Rapenne, K. Yasuhara
[ doi:10.1039/D3CC05167F ]
" Multiply engaged molecular gear composed of Ce(IV) double-decker of a triptycene-functionalized porphyrin," Dalton Trans., vol.52, pp11797-11801, 9 Aug. 2023
T. Nishino, M. Fukumura, K. Yasuhara, S. Katao, G. Rapenne
[ doi:10.1039/D3DT02443A ]
"Multiply Engaged Molecular Gear composed of Cerium (IV) Double-Decker of a triptycene-functionalized Porphyrin," Dalton Transactions, vol.52, pp11797-11801, 9 Aug. 2023
T. Nishino, M. Fukumura, S. Katao, K, Kazuma Yasuhara, G. Rapenne
[ doi:10.1039/D3DT02443A ]
"自然にまなぶ抗菌・抗ウィルス高分子," 高分子, vol.72, pp327-330, 2023.7
安原 主馬
"Hydrothermal Preparation of Faceted Vesicles Made of Span 40 and Tween 40 and Their Characterization," Applied Sciences, vol.13, pp6893, 7 Jun. 2023
Toshinori Shimanouchi, Yui Komori, Kazuki Toramoto, Keita Hayashi, Kazuma Yasuhara, Ho-Sup Jung, Yukitaka Kimura
[ doi:10.3390/app13126893 ]
"Conversion of Glycerol to Lactic Acid by Using Platinum-supported Catalyst Combined with Phosphatidylcholine Vesicles," Chemistry Letters, 2023, vol.52, pp426-429, 5 Jun. 2023
Toshinori Shimanouchi, Yuki Takahashi, Kazuma Yasuhara, Yukitaka Kimur
[ doi:10.1246/cl.230117 ]
" Extended tripodal hydrotris(indazol-1-yl)borate ligands as ruthenium-supported cogwheels for on-surface gearing motions," Chem. Eur. J., vol.29, 25 Jan. 2023
K. Omoto, M. Shi, K. Yasuhara, C. Kammerer, G. Rapenne
[ doi:10.1002/chem.202203483 ]
"Extended Tripodal Hydrotris(indazol-1-yl)borate Ligands as Ruthenium-Supported Cogwheels for On-Surface Gearing Motions," Chemistry - A European Journal, vol.29, ppe202203483, 25 Jan. 2023
K. Omoto, M. Shi, K. Yasuhara, Claire Kammerer, Gwenael Rapenne
[ doi:10.1002/chem.202203483 ]
"Possible Role of Vesicles on Metallocatalytic Reduction Reaction of 5-Hydroxymethylfurfural to 2,5-Dimethylfuran," Compounds, vol.2, pp321-333, 22 Nov. 2022
T. Shimanouchi, Y. Takahashi, K. Hayashi, K. Yasuhara, Y. Kimura
[ doi:10.3390/compounds2040027 ]
"Thermally responsive morphological changes of layered coordination polymers induced by disordering/ordering of flexible alkyl chains," Dalton Trans., vol.51, pp17967-17972, 1 Nov. 2022
K. Omoto, S. Aoyama, T. Galica, E. Nishibori, S. Kato, K. Yasuhara, G. Rapenne
[ doi:10.1039/D2DT03142F ]
"Biomimetic Antimicrobial Polymers – Design, Characterization, Antimicrobial and Novel Applications," WIREs Nanomedicine & Nanobiotechnology, vol.15, ppe1866, 27 Oct. 2022
H. Takahashi, I. Sovadinova, K. Yasuhara, S. Vemparala, G. A. Caputo, K. Kuroda
"Creation of supramolecular biomembrane by the bottom-up self-assembly: Where material science meets biophysics," Biophysics and Physicobiology, vol.19, ppe190043, 20 Oct. 2022
K. Yasuhara, K. Morigaki
[ doi:10.2142/biophysico.bppb-v19.0043 ]
"Peptide modification on the interior surface of red blood cell ghosts for construction of catalytic reactors," Chemical Communications, vol.58, pp12220-12223, 7 Oct. 2022
9. H. Matsumoto, K. Okuichi, H. Imamura, K. Yasuhara, M. Kato, T. Koshiyama
[ doi:10.1039/D2CC05013G ]
"Biomimetic Antimicrobial Polymers – Design, Characterization, Antimicrobial and Novel Applications WIREs Nanomedicine & Nanobiotechnology ," WIREs Nanomedicine & Nanobiotechnology , Sep. 2022
Haruko Takahashi, Iva Sovadinova, Kazuma Yasuhara, Satyavani Vemparala, Gregory A. Caputo, Kenichi Kuroda
"生体膜に作用する機能性分子のバイオミメティック・デザイン," 材料表面, vol.7, pp83-91, 2022.8.25
安原 主馬
"Amyloid-β aggregates induced by β-cholesteryl glucose-embedded liposomes," Biochimica et Biophysica Acta - Proteins and Proteomics 2022, 1870, 140816., vol.1870, pp140816, 1 Aug. 2022
T. Shimanouchi, Y. Sano, K. Yasuhara, Y. Kimura
[ doi:10.1016/j.bbapap.2022.140816 ]
"第2回国際ナノカーレース参戦記 -ナノメートルスケールのル・マン24時間耐久レース," 化学, vol.77, pp44-48, 2022.7.20
西野 智雄, 安原 主馬, Gwénaël Rapenne
"Nanofluidic Model Membrane for the Single-Molecule Observation of Membrane Proteins," Langmuir, vol.38, pp7234-7243, 31 May. 2022
Ryota Komatsu, Yasushi Tanimoto, Koji Ando, Kazuma Yasuhara, Yasuhiko Iwasaki, Fumio Hayashi, Kenichi Morigaki
[ doi:10.1021/acs.langmuir.2c00724 ]
"CPL on/off control of an assembled system by water soluble macrocyclic chiral sources with planar chirality," Chem. Sci. , vol.13, pp5846-5853, 30 Mar. 2022
S. Fa, T. Tomita, K. Wada, K. Yasuhara, S. Ohtani, K. Kato, M. Gon, K. Tanaka, T. Kakuta, T. Yamagishi, T. Ogoshi
[ doi:10.1039/D2SC00952H ]
"An Antimicrobial Peptide-Mimetic Methacrylate Random Copolymer Induces Domain Formation in a Model Bacterial Membrane," J. Membrane Biol, 18 Feb. 2022
K. Yasuhara, M. Tsukamoto, J. Kikuchi, K. Kuroda
[ doi:10.1007/s00232-022-00220-6 ]
"An antimicrobial peptide-mimetic methacrylate random copolymer induces domain formation in a model bacterial membrane," Journal of Membrane Biology, 18 Feb. 2022
Kazuma Yasuhara, Manami Tsukamoto, Jun-ichi Kikuchi, Kenichi Kuroda
[ doi:10.1007/s00232-022-00220-6 ]
"Designed amphiphiles for cell membrane mimetic nanoarchitecture," in Nanoscience & Nanotechnology Series No. 55. Concepts and Design of Materials Nanoarchitectonics, pp361-380, 16 Feb. 2022
K. Yasuhara, K. Omoto, T. Nishino, G. Rapenne
[ doi:10.1039/9781788019613 ]
"完熟トマトはなぜあんなに赤い?〜カロテノイド微粒子中の歪んだ現実〜," 現代化学, vol.606, pp37-39, 2022.1.25
鈴木 龍樹, 安原 主馬, 出口 茂
"Effect of Molecular Distortion on the Optical Properties of Carotenoid-Based Nanoparticles," J. Phys. Chem. , vol.126, pp2607-2613, 21 Jan. 2022
R. Suzuki, K. Yasuhara, S. Deguchi
[ doi:10.1021/acs.jpcc.1c08572 ]
"Molecular vehicles based on a polyaromatic or porphyrinic chassis," J. Synth. Org. Chem. Jpn , vol.79, pp1050-1055, 1 Nov. 2021
T. Nishino, C.J. Martin, K. Yasuhara, G. Rapenne
[ doi:10.5059/yukigoseikyokaishi.79.1050 ]
"Mechanistic Study of Membrane Disruption by Antimicrobial Methacrylate Random Copolymers by the Single Giant Vesicle Method," Langmuir, vol.37, pp9982-9995, 11 Aug. 2021
M. Tsukamoto, E. Zappala, G. A. Caputo, J. Kikuchi, K. Najarian, K. Kuroda, K. Yasuhara
[ doi:10.1021/acs.langmuir.1c01047 ]
"脂質膜のナノディスク化技術と熱測定への応用," 熱測定, vol.48, pp108-113, 2021.7.25
安原 主馬
"Microfluidic and hydrothermal preparation of vesicles using sorbitan monolaurate/polyoxyethylene (20) sorbitan monolaurate (Span 20/Tween 20)," Colloids Surf. B Biointerfaces, vol.205, pp11836, 11 May. 2021
Toshinori Shimanouchi, Tetsuya Hayashi, Kazuki Toramoto, Saki Fukuma, Keita Hayashi, Kazuma Yasuhara, Yukitaka Kimura
[ doi:10.1016/j.colsurfb.2021.111836 ]
"Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells," Developmental Cell, vol.22, no.56, pp842-859, 22 Mar. 2021
Tamako Nishimura, Takuya Oyama, Hooi Ting Hu, Toshifumi Fujioka, Kyoko Hanawa-Suetsugu, Kazutaka Ikeda, Sohei Yamada, Hiroki Kawana, Daisuke Saigusa, Hiroki Ikeda, Rie Kurata, Kayoko Oono-Yakura, Manabu Kitamata, Kazuki Kida, Tomoya Hikita, Kiyohito Mizutani, Kazuma Yasuhara, Yuko Mimori-Kiyosue, Chitose Oneyama, Kazuki Kurimoto, Yoichiroh Hosokawa, Junken Aoki, Yoshimi Takai, Makoto Arita, Shiro Suetsugu
[ NAISTレポジトリ ] [ doi:10.1016/j.devcel.2021.02.029. ]
"pH-Dependent ion permeability control of a modified amphotericin B channel through metal complexation," Chem. Commun., vol.57, pp2895-2898, 9 Feb. 2021
T. Koshiyama, Y. Inoue, S. Asada, K, Kawahara, S. Ide, K. Yasuhara, M. Ohba
[ doi:10.1039/D0CC08368B ]
"アミロイドタンパク質解析のための脂質ナノディスク," 膜(MEMBRANE), vol.46, pp32-37, 2021.1.26
安原 主馬
"New lipid membrane technologies for reconstitution, analysis, and utilization of 'living' membrane proteins," Biophysics and Physicobiology, 4 Sep. 2020
Kazuma Yasuhara, Kenichi Morigaki
[ doi:10.2142/biophysico.BSJ-2020021 ]
"Regulation of caveolae through cholesterol-depletion dependent tubulation by PACSIN2/Syndapin II," Journal of Cell Science, 2 Sep. 2020
Aini Gusmira, Kazuhiro Takemura, Shin Yong Lee, Takehiko Inaba, Kyoko Hanawa-Suetsugu, Kayoko Oono-Yakura, Kazuma Yasuhara, Akio Kitao, Shiro Suetsugu
[ doi:10.1242/jcs.246785 ]
"Dipolar Nanocars Based on a Porphyrin Backbone," Chemistry - A European Journal, vol.26, pp12010-12018, 12 Jun. 2020
Toshio Nishino, Colin J. Martin, Hiroki Takeuchi, Florence Lim, Kazuma Yasuhara, Yohan Gisbert, Seifallah Abid, Nathalie Saffon-Merceron, Claire Kammerer, Gwenael Rapenne
[ doi:10.1002/chem.202001999 ]
"Dipolar nanocars based on a porphyrin backbone," Chem. Eur. J. , vol.26, pp12010-12018, 12 Jun. 2020
T. Nishino, C. J. Martin, H. Takeuchi, F. Lim, K. Yasuhara, Y. Gisbert, S. Abid, N. Saffon‐Merceron, C. Kammerer, G. Rapenne
[ doi:10.1002/chem.202001999 ]
"細胞膜にはたらく両親媒性ポリマーのバイオミメティック・デザイン," オレオサイエンス, vol.20, pp275-282, 2020.6
安原 主馬
"Protein surface charge effect on 3D domain swapping in cells for c-type cytochromes," BBA Proteins and Proteomics, vol.1867, pp140265, 19 Aug. 2019
Hongxu Yang, Masaru Yamanaka, Satoshi Nagao, Kazuma Yasuhara, Naoki Shibata, Yoshiki Higuchi
[ doi:10.1016/j.bbapap.2019.140265 ]
"Determination of Proton Concentration at Cardiolipin-Containing Membrane Interfaces and Its Relation with the Peroxidase Activity of Cytochrome c," Chem. Sci., vol.10, 6 Aug. 2019
Partha Pratim Parui, Yeasmin Sarakar, Rini Majumder, Sanju Das, Hongxu Yang, Kazuma Yasuhara
[ NAISTレポジトリ ]
"Biomimetic and technomimetic single molecular machines," Chem. Lett. 2019, 48, 299-308. , vol.48, pp299-308, 5 Apr. 2019
C. Kammerer, G. Erbland, Y. Gisbert, T. Nishino, K. Yasuhara, G. Rapenne
"支部発 話題欄 細胞膜機能を探る脂質ナノディスク 生きた膜タンパク質の解析をめざした新しいプラットフォーム," 化学と工業, vol.72, pp240-241, 2019.3
安原 主馬
"A cationic polymethacrylate-copolymer acts as an agonist for β-amyloid and an antagonist for amylin fibrillation," Chemical Science, vol.10, pp3976-3986, 27 Feb. 2019
Bikash R. Sahoo, Takuya Genjo, Takahiro W. Nakayama, Andrea K. Stoddard, Toshio Ando, Kazuma Yasuhara, Carol A. Fierke, Ayyalusamy Ramamoorthy
"Anticancer polymers designed for killing dormant prostate cancer cells," Scientific Reports, vol.9, pp1096-1096, 31 Jan. 2019
Haruko Takahashi, Kenji Yumoto, Kazuma Yasuhara, Enrico T. Nadres, Yutaka Kikuchi, Russell S. Taichman, Kenichi Kuroda
"Biomimetic and Technomimetic Single Molecular Machines ," Chem. Lett., vol.48, pp299-308, 23 Jan. 2019
C. Kammerer, G. Erbland, Y. Gisbert, T. Nishino, K. Yasuhara, G. Rapenne
[ doi:10.1246/cl.181019 ]
"Biomimetic and technomimetic single molecular machines," Chem. Lett., vol.48, pp299-308, Jan. 2019
C. Kammerer, G. Erbland, Y. Gisbert, T. Nishino, K. Yasuhara, G. Rapenne
[ doi:10.1246/cl.181019 ]
"Light-triggered Hydrophilic Drug Release from Liposomes through Removal of a Photoabile Protecting Group," RSC Adv., vol.9, pp166-171, Dec. 2018
Y. Goto, M. Ueda, K. Sugikawa, K. Yasuhara, A. Ikeda
[ doi:10.1039/c8ra08584f ]
"Alzheimer's amyloid-beta intermediates generated using polymer-nanodiscs," Chemical Communications, vol.54, pp12883-12886, 22 Oct. 2018
Bikash R. Sahoo, Takuya Genjo, Michael Bekier, II, Sarah J. Cox, Andrea K. Stoddard, Magdalena Ivanova, Kazuma Yasuhara, Carol A. Fierke, Yanzhuang Wang, Ayyalusamy Ramamoorthy
"From the Synthesis of a Molecular Wheel to the First Nanocar Race," pp317-320, 12 Sep. 2018
G.Rapenne, K.Yasuhara
"Biomimetic antimicrobial polymers: recent advances in molecular design," Polymer Chemistry, vol.9, pp2407-2427, 23 Apr. 2018
C. Ergene, K. Yasuhara, E.. F. Palermo
"脂質ナノディスクを自発形成する膜活性ポリマーのデザイン," C&I Commun, vol.43(1), pp29-31, 2018.3.10
安原 主馬
"Aggregation of Cationic Amphiphilic Block and Random Copoly(vinyl ether)s with Antimicrobial Activity," Polymers, vol.10(1), pp93-93, 2018.1.19
安原 主馬
"Spontaneous Lipid Nanodisc Fomation by Amphiphilic Polymethacrylate Copolymers," J. Am. Chem. Soc., vol.139(51), pp18657-18663, 24 Nov. 2017
K. Yasuhara, J. Arakida, T. Ravula, S. K. Ramadugu, B. Sahoo, J. Kikuchi, A. Ramamoorthy
"Growth of Anisotropic Gold Nanoparticle Assemblies by Fusion of Liposomes," Materials, vol.10(11), pp1317-1317, 17 Nov. 2017
K. Sugikawa, T. Kadota, K. Matsuo, K. Yasuhara, A. Ikeda
"Tubulation of Liposomes via the Interaction of Supramolecular Nanofibers," Chemical Communications, vol.53(73), pp10140-10143, 2017.9.18
K. Sugikawa, Y. Takamatsu, T. Kakigi, K. Yasuhara, A. Ikeda
"Tubulation of Liposomes via the Interaction of Supramolecular Nanofibers," 18 Aug. 2017
K. Sugikawa, Y. Takamatsu, T. Kakigi, K. Yasuhara, A. Ikeda
"Controlled synthesis of pillar[6]arene-based hexagonal cylindrical structures on an electrode surface by electrochemical oxidation," Chemical Communications, vol.53, pp7454-7456, 2017.7.11
C. Tsuneishi, Y. Koizumi, R. Sueto, H. Nishiyama, K. Yasuhara, T. Yamagishi, T. Ogoshi, I. Tomita, S. Inagi
"Controlled synthesis of pillar[6]arene-based hexagonal cylindrical structures on an electrode surface by ," Chem. Commun., vol.53, pp7454-7456, 25 May. 2017
C. Tsuneishi, Y. Koizumi, R. Sueto, H. Nishiyama, K. Yasuhara, T. Yamagishi, T. Ogoshi, I. Tomita, S. Inagi
"Effects of exosome-like vesicles on cumulus expansion in pigs in vitro," J Reprod Dev, vol.63(1), pp51-58, 5 Feb. 2017
Yuta Matsuno, Asuka Onuma, Yoshie A Fujioka, Kazuma Yasuhara, Wataru Fujii, Kunihiko Naito, Koji
"Reversible Vesicle-to-Disk Transitions of Liposomes Induced by Self-Assembly of Water-Soluble Porphyrins," Langmuir, vol.33(4), pp1023-1029, 31 Jan. 2017
K. Sugikawa, Y. Takamatsu, K. Yasuhara, M. Ueda, A. Ikeda
"Reversible Vesicle-to-Disk Transitions of Liposomes Induced by Self-Assembly of Water-Soluble ," Langmuir, vol.33(4), pp1023-1029, 5 Jan. 2017
K. Sugikawa, Y. Takamatsu, K. Yasuhara, M. Ueda, A. Ikeda
"Effects of exosome-like vesicles on cumulus expansion in pigs in vitro," J Reprod Dev, vol.in press, Aug. 2016
Yuta Matsuno, Asuka Onuma, Yoshie A Fujioka, Kazuma Yasuhara, Wataru Fujii, Kunihiko Naito, Koji Sugiura
"Spherical Vesicles Formed by Co-Assembly of Cyclic Pentagonal Pillar[5]quinone with Cyclic Hexagonal Pillar[6]arene," J. Am. Chem. Soc., vol.138(26), pp8064-8067, 23 Jun. 2016
Tomoki Ogoshi, Ryuta Sueto, Kumiko Yoshikoshi, Kazuma Yasuhara, Tada-aki Yamagishi
"Anisotropic Self-Assembly of Citrate-Coated Gold Nanoparticles on Fluidic Liposomes," Angewandte Chemie International edition , vol.55(12), pp4059-4063, Mar. 2016
Kouta Sugikawa, Tatsuya Kadota, Kazuma Yasuhara, Atsushi Ikeda
"Porphyrin-uptake in liposomes and living cells using an exchange method with cyclodextrin," RSV Advances, vol.5, pp105279-105287, Dec. 2015
Atsushi Ikeda, Shodai Hino, Tomoya Mae, Yuki Tsuchiya, Kouta Sugikawa, Manami Tsukamoto, Kazuma Yasuhara, Hajime Shigeto, Hisakage Funabashi, Akio Kuroda, Motofusa Akiyama
"Lipid-membrane-incorporated hydrophobic photochromic molecules prepared by the exchange method using cyclodextrins ," Organic&Biomolecular Chemistry, vol.13, pp6175-6182, 27 May. 2015
Atsushi Ikeda, Shodai Hino, Kengo Ashizawa, Kouta Sugikawa, Jun-ichi Kikuchi, Manami Tsukamoto, Kazuma Yasuhara
"Kinetic study of all-or-none hemolysis induced by cationic amphiphilic polymethacrylates with antimicrobial activity," Chinese Chemical Letters(CCL), vol.26(04), pp479-484, Apr. 2015
Kazuma Yasuhara, Kenichi Kuroda
"[70]Fullerenes Assists the Formation of Phospholipid Bicelles at Low Lipid Concentrations," Langmuir, vol.30(41), pp12315-12320, 2014.10.2
Atsushi Ikeda, Kazuya Kiguchi, Tomohiro Hida, Kazuma Yasuhara, Kazuyuki Nobusawa, Motofusa Akiyama, Wataru Shinoda
"Modulation of raft domains in a lipid bilayer by boundary-active curcumin," Chemical Communications , vol.50, pp3427-3430, 4 Apr. 2014
Manami Tsukamoto, Kenichi Kuroda, Ayyalusamy Ramamoorthy, Kazuma Yasuhara
"Solubilization of genistein by caseinate micellar system," J Oleo Sci, vol.63(4), pp413-422, 5 Mar. 2014
Anjani G, Ohta A, Yasuhara K, Asakawa T
"Morphological change of cell membrane by interaction with domain-swapped cytochrome c oligomers," Chembiochem, vol.15(4), pp517-521, 3 Mar. 2014
Junedi S, Yasuhara K, Nagao S, Kikuchi J, Hirota S.
"Dynamic Behaviour in Giant Unilamellar Vesicles induced by the Uptake of [70] Fullerene," Chem.Commun , vol.50(11), pp1288-1291, 9 Feb. 2014
Atsushi Ikeda, Hida, Tomohiro, Tsukamoto, Manami, Junichi Kikuchi, Kazuma Yasuhara
"Synthetic cell division system: Controlling equal vs. unequal divisions by design," Scientific Reports, vol.3, pp3475, 11 Dec. 2013
Yoichi Sato, Kazuma Yasuhara, Jun-ichi Kikuchi, Thomas N. Sato
"Molecular Design, Structures, and Activity of Antimicrobial Peptide-Mimetic Polymers," Macromolecular Bioscience, vol.13, pp1285-1299, Oct. 2013
Takahashi Haruko, Edmund F. Palermo, Kazuma Yasuhara, Gregory A. Caputo, Kuroda Kenichi
"セラミック表面によって安定化された脂質二分子膜ナノディスクの形成," C&I Commun., vol.38, no.1, pp29-32, 2013.4
安原 主馬
"Unique concentration dependence on the fusion of anionic liposomes induced by polyethyleneimine," Colloid and Surfaces A, vol.415, pp461-467, 5 Dec. 2012
Kazuma Yasuhara, Tsukamoto, Manami, Yasutaka Tsuji, Junichi Kikuchi
"Spontaneously formed semipermeable organic–inorganic hybrid vesicles permitting molecular weight selective transmembrane passage," Chem. Commun., vol.49, pp665-667, 22 Oct. 2012
Kazuma Yasuhara, Kawataki, Takahiro, Okuda, Shizuyo, Oshima Shohei, Junichi Kikuchi
"Thermal stability of synthetic lipid bicelles encompassed by siloxane surfaces as organic-inorganic hybrid nanodiscs," Chemistry Letters, vol.41, pp1223-1225, 13 Oct. 2012
Kazuma Yasuhara, Hayashi, Hiroki, Junichi Kikuchi
"注目の論文 脂質膜は名”翻訳”家?!," 化学, vol.67, no.7, pp59, 2012.7
安原主馬
"Advantages and Potential of Lipid Membrane-Incorporating Fullerenes Prepared by the Exchange Reaction Method," Chem. -Asian J., vol.7, no.3, pp605, May. 2012
A. Ikeda, M. Mori, K. Kiguchi, K. Yasuhara, J. Kikuchi, K. Nobusawa, M. Akiyama, M. Hashizume, T. Ogawa, T. Takeya
"Advantages and Potential of Lipid-Membrane-Incorporating Fullerenes Prepared by the Fullerene-Exchange Method.," Chem Asian J., vol.7, no.3, pp605, Mar. 2012
Ikeda A, Mori M, Kiguchi K, Yasuhara K, Kikuchi JI, Nobusawa K, Akiyama M, Hashizume M, Ogawa T, Takeya T.
"ANTIMICROBIAL ACTION OF POLYMETHACRYLATE DERIVATIVE WITH DIPICOLYLAMINE SIDECHAINS," Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem., vol.53(1), pp554-554, Mar. 2012
Yasuhara, K., Ikematsu, C., Tsukamoto, M., 菊池 純一
"Remarkable Long-term Stability of Cerasome as an Organic-Inorganic Hybrid Nano-container for Water-soluble Macromolecules," Chem. Lett, vol.40, no.5, pp461-463, May. 2011
Kawataki, Takahiro, Kazuma Yasuhara, Junichi Kikuchi
"Switching of the Enzymatic Activity Synchronized with Signal Recognition by an Artificial DNA Receptor on a Liposomal Membrane," Org. Biomol. Chem, vol.9, pp2397, Apr. 2011
Sasaki, Yoshihiro, Mukai, Masaru, Kawasaki, Akihiro, Kazuma Yasuhara, Junichi Kikuchi
"Specific delivery of transport vesicles mediated by complementary recognition of DNA signals with membrane-bound oligonucleotide lipids," Supramol. Chem, vol.23, no.3-4, pp218, Apr. 2011
Kazuma Yasuhara, Wang, Zhong-hua, Ishikawa,Takahiro, Junichi Kikuchi, Sasaki Yoshihiro, Hiyama, Satoshi, Moritani,Yuki, Suda, Tatsuya
"細菌の細胞膜に作用するポリマー抗菌剤の設計," バイオマテリアルー生体材料, vol.29(4), pp282-286, 2011.4
安原 主馬
"Synthesis of Organic-Inorganic Hybrid Bicelles - Lipid Bilayer Nanodiscs Encompassed by Siloxane Surfaces," Chem. Commun, vol.47, pp4691, Mar. 2011
Kazuma Yasuhara, Miki, Shohei, Nakazono, Hajime, Ohta, Akio, Junichi Kikuchi
"抗感染性・抗菌性マテリアル(6): 細菌の細胞膜に作用するポリマー抗菌剤の設計," バイオマテリアル, 2011
安原主馬
"Budding and Fission of Cationic Binary Lipid Vesicles Induced by the Incorporation of Pyranine," Chem. Lett.., vol.39, no.1, pp54, 1 Jan. 2010
Wang, ZH, Yasuhara, K, Ito, H, Mukai, M, Kikuchi, J
[ doi:10.1246/cl.2010.54 ]
"Effect of Functional Groups on Incorporation Behavior of Amino Acid-Type Surfactant into Phospholipid Vesicle Membrane," J. Oleo Sci., vol.58, no.12, pp607, 1 Dec. 2009
Ohta, A, Miyazato, Y, Sasaki, H, Yasuhara, K, Asakawa, T
"自然のしくみに学ぶ次世代抗菌マテリアル 細菌の細胞膜に働く抗菌ポリマーの設計," 化学, vol.64, no.3, pp72, 2009.3.1
安原主馬, 菊池 純一
"Fluorescent sensor responsive to local viscosity and its application to the imaging of liquid-ordered domain in lipid membranes," Colloids Surf. B: Biointerfaces, vol.67, no.1, pp145, 1 Nov. 2008
Yasuhara, K, Sasaki, Y, Kikuchi, J
[ doi:10.1016/j.colsurfb.2008.08.004 ]
"Construction of Artificial Cell Membranes having Lipid Microdomains for Molecular Information Processing," Proceedings of 2008 International Symposium on Micro-NanoMechatronics and Human Science, 1 Nov. 2008
K. Yasuhara, Z. Wang, K. Hirata, Y. Sasaki, J. Kikuchi
"A photo-responsive cholesterol capable of inducing a morphological transformation of the liquid-ordered microdomain in lipid bilayers," Colloid Polym. Sci., vol.286, no.14-15, pp1675, 1 Oct. 2008
Yasuhara, K, Sasaki, Y, Kikuchi, J
[ doi:10.1007/s00396-008-1936-5 ]
"Interaction of Amphiphilic Polymers with Lipid Vesicles," Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem., vol.49(2), pp432-433, Aug. 2008
Kazuma Yasuhara, Kenichi Kuroda
"Fluorescence study on the domain formation of N-dodecanoyl-L-tryptophan within a liposome membrane," Colloid Polym. Sci., vol.285, no.2, pp239, 25 Aug. 2006
Yasuhara, K, Shimanouchi, T, Umakoshi, H, Kuboi, R
[ doi:10.1007/s00396-006-1547-y ]
"Evaluation of temperature and guanidine hydrochloride-induced protein-liposome interactions by using immobilized liposome chromatography," Biochem. Eng. J., vol.29, no.3, pp174, 15 Apr. 2006
Yoshimoto, N, Yoshimoto, M, Yasuhara, K, Shimanouchi, T, Umakoshi, H, Kuboi, R
[ doi:10.1016/j.bej.2005.08.030 ]
"Unique incorporation behavior of amino acid-type surfactant into phospholipid vesicle membrane," Colloid Polym. Sci., vol.283, no.9, pp987, 19 Jan. 2005
Yasuhara, K, Ohta, A, Asakura, Y, Kodama, T, Asakawa, T, Miyagishi, S
[ doi:10.1007/s00396-004-1252-7 ]
受賞
"令和6年度科学奨励賞," 日本化学会 コロイドおよび界面化学部会 , 2024.9.18
安原 主馬
"Springe-Nature PPS Poster Award," The 31st International Conference on Photochemistry, 25 Jul. 2023
Magin Benedict Fernandez Ferrer, Daiyu Harada, Kazuma Yasuhara, Takayuki Yanagida, Noriaki Kawaguchi, Louis Marine, Remi Metivier, Clemence Allain, Keitaro Nakatani, Tsuyoshi Kawai
"膜シンポジウム 2019 学生賞," Nov. 2019
Hao Jinyu, Yuma Mitsuyoshi, Gwenael Rapenne, Kazuma Yasuhara
"第12回バイオ関連化学シンポジウム 講演賞," 第12回バイオ関連化学シンポジウム, 2018.9.11
安原 主馬
"平成28年度NAIST学術奨励賞," 奈良先端科学技術大学院大学, 2017.2.25
安原 主馬
"若手研究者奨励講演賞," 第26回バイオ・高分子シンポジウム, 2016.8.2
安原 主馬
"Best Poster Award - Bronze Prize," 2015 GIST-NAIST-NCTU Joint Symposium, 20 Nov. 2015
K. Yasuhara, T. Nakano, J. Kikuchi
"優秀講演賞(学術)," 日本化学会第93春季年会, 2013.3.23
安原 主馬, 大島匠平, 菊池 純一
"2012 GIST-NAIST-NCTU Joint Symposium on Interdisciplinary Nanoscience & Beyond-bronze award," 2012 GIST-NAIST-NCTU Joint Symposium on Interdisciplinary Nanoscience & Beyond, 21 Nov. 2012
Manami Tsukamoto, Kazuma Yasuhara, Kenichi Kuroda, Junichi Kikuchi
"Best poster award," International Symposium on Molecular Nanotechnology, Dec. 2010
安原 主馬
所属学協会
日本ゾル-ゲル学会
アメリカ生物物理学会
アメリカ化学会
高分子学会
日本化学会 生体機能関連化学部会
日本化学会 コロイドおよび界面化学部会
日本化学会
資料

Gwenael Rapenne

職位 教授
領域 物質創成科学領域 基幹研究室
研究室 バイオ・テクノミメティック分子科学

バイオミメティックスおよびテクノミメティクスに基づく分子マシンの設計 ・ 合成とナノ機械工学および生物応用に関する研究・教育を行う。

西野 智雄

職位 助教
領域 物質創成科学領域 基幹研究室
研究室 バイオ・テクノミメティック分子科学

バイオミメティックスおよびテクノミメティクスに基づく分子マシンの設計 ・ 合成とナノ機械工学および生物応用に関する研究・教育を行う。

服部 陽平

職位 特任助教
領域 物質創成科学領域 基幹研究室
研究室 バイオ・テクノミメティック分子科学

バイオミメティックスおよびテクノミメティクスに基づく分子マシンの設計 ・ 合成とナノ機械工学および生物応用に関する研究・教育を行う。