塩﨑 一裕

所属 役員会
職位 学長
学位 理学博士(京都大学)
研究室 役員
研究キーワード
研究分野
ライフサイエンス / 細胞生物学 /
研究室概要
学術論文
"Fission yeast Pib2 localizes to vacuolar membranes and regulates TOR complex 1 through evolutionarily conserved domains," FEBS Letters, Jul. 2024
Yuichi Morozumi, Yumi Hayashi, Cuong Minh Chu, Fajar Sofyantoro, Yutaka Akikusa, Tomoyuki Fukuda, Kazuhiro Shiozaki
[ doi:10.1002/1873-3468.14980 ]
"Rapamycin-sensitive mechanisms confine the growth of fission yeast below the temperatures detrimental to cell physiology," iScience, vol.27, no.1, pp108777, Jan. 2024
Yuichi Morozumi, Fontip Mahayot, Nakase Yukiko, Jia Xin Soong, Sayaka Yamawaki, Fajar Sofyantoro, Yuki Imabata, Arisa H. Oda, Miki Tamura, Shunsuke Kofuji, Yutaka Akikusa, Ayu Shibatani, Kunihiro Ohta, Kazuhiro Shiozaki
[ doi:10.1016/j.isci.2023.108777. ]
"Fission Yeast TORC1 Promotes Cell Proliferation through Sfp1, a Transcription Factor Involved in Ribosome Biogenesis," Molecular and Cellular Biology, vol.43, no.12, pp675-692, Dec. 2023
Yen Teng Tai, Tomoyuki Fukuda, Yuichi Morozumi, Hayato Hirai, Arisa H. Oda, Yoshiaki Kamada, Yutaka Akikusa, Tomotake Kanki, Kunihiro Ohta, Kazuhiro Shiozaki
[ doi:10.1080/10985549.2023.2282349. ]
"Rapamycin-sensitive mechanisms confine the growth of fission yeast below the temperatures detrimental to cell physiology," bioRxiv, 5 May. 2023
Yuichi Morozumi, Fontip Mahayot, Nakase Yukiko, Jia Xin Soong, Sayaka Yamawaki, Fajar Sofyantoro, Yuki Imabata, Arisa H. Oda, Miki Tamura, Shunsuke Kofuji, Yutaka Akikusa, Kunihiro Ohta, Kazuhiro Shiozaki
"Fission yeast TOR complex 1 phosphorylates Psk1 through an evolutionarily conserved interaction mediated by the TOS motif," Journal of Cell Science, Sep. 2021
Yuichi Morozumi, Ai Hishinuma, Suguru Furusawa, Fajar Sofyantoro, Hisashi Tatebe
[ doi:10.1242/jcs.258865 ]
"Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase," eLife, vol.10, ppe60969, 3 Feb. 2021
Tomoyuki Fukuda, Fajar Sofyantoro, Yen Teng Tai, Kim Hou Chia, Takato Matsuda, Takaaki Murase, Yuichi Morozumi, Hisashi Tatebe, Tomotake Kanki, Kazuhiro Shiozaki
[ doi:10.7554/eLife.60969 ]
"Conserved and divergent mechanisms that control TORC1 in yeasts and mammals," Genes, vol.12, no.1, pp88, 12 Jan. 2021
Yuichi Morozumi, Kazuhiro Shiozaki
[ doi:10.3390/genes12010088 ]
"Maf1-dependent transcriptional regulation of tRNAs prevents genomic instability and is associated with extended lifespan," Aging Cell, vol.19, ppe13068, Feb. 2020
Mihir Shetty, Chiaki Noguchi, Sydney Wilson, Esteban Martinez, Kazuhiro Shiozaki, Christian Sell, Joshua Chang Mell, Eishi Noguchi
[ doi:10.1111/acel.13068 ]
"Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge," Nature Communications, vol.11, no.1, 17 Jan. 2020
Hisashi Tatebe, Chew Theng Lim, Hiroki Konno, Kazuhiro Shiozaki, Akira Shinohara, Takayuki Uchihashi, Asako Furukohri
[ doi:10.1038/s41467-019-14025-0 ]
"Modulation of TOR complex 2 signaling by the stress-activated MAPK pathway in fission yeast," Journal of Cell Science, 2 Sep. 2019
Susumu Morigasaki, Lit Chein Chin, Tomoyuki Hatano, Midori Emori, Mika Iwamoto, Hisashi Tatebe, Kazuhiro Shiozaki
[ doi:10.1242/jcs.236133 ]
"Reciprocal regulation of TORC signaling and tRNA modifications by Elongator enforces nutrient-dependent cell fate," Science Advances, vol.5, no.6, ppeaav0184, 19 Jun. 2019
Julie Candiracci, Valerie Migeot, Yok-Hian Chionh, Fanelie Bauer, Thomas Brochier, Brandon Russell, Kazuhiro Shiozaki, Peter Dedon, Damien Hermand
[ doi:10.1126/sciadv.aav0184 ]
"Nutrient Signaling via the TORC1-Greatwall-PP2AB55δ Pathway Responsible for the High Initial Rates of Alcoholic Fermentation in Sake Yeast Strains of Saccharomyces cerevisiae," Applied and Environmental Microbilogy, 19 Oct. 2018
Daisuke Watanabe, Takuma Kajihara, Yukiko Sugimoto, Kenichi Takagi, Megumi Mizuno, Yan Zhou, Jiawen Chen, Kojiro Takeda, Hisashi Tatebe, Kazuhiro Shiozaki, Nobushige Nakazawa, Shingo Izawa, Takeshi Akao, Hitoshi Shimoi, Tatsuya Maeda, Hiroshi Takagi
[ NAISTレポジトリ ] [ doi:10.1128/AEM.02083-18 ]
"The Rag GTPase-Ragulator complex attenuates TOR complex 1 signaling in fission yeast," Autophagy, vol.14, pp1105-1106, May. 2018
Tomoyuki Fukuda, Kazuhiro Shiozaki
[ doi:10.1080/15548627.2018.1444313 ]
"Ragulator and GATOR1 complexes promote fission yeast growth by attenuating TOR complex 1 through Rag GTPases," eLife, vol.6, ppe30880, Dec. 2017
Kim Hou Chia, Tomoyuki Fukuda, Fajar Sofyantoro, Takato Matsuda, Takamitsu Amai, Kazuhiro Shiozaki
[ doi:10.7554/eLife.30880 ]
"Evolutionary Conservation of the Components in the TOR Signaling Pathways," Biomolecules, vol.7, no.4, 1 Nov. 2017
Hisashi Tatebe, Kazuhiro Shiozaki
[ doi:10.3390/biom7040077 ]
"Guest Editor for the Special Issue - TOR Signaling Pathway," Biomolecules, vol.7, no.3, Aug. 2017
Kazuhiro Shiozaki
"PP2C," Encyclopedia of Signaling Molecules, pp1-6, 17 Mar. 2017
Hisashi Tatebe, Kazuhiro Shiozaki
[ doi:10.1007/978-1-4614-6438-9_249-1 ]
"Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit," eLIFE, vol.6, ppe19594, 7 Mar. 2017
Hisashi Tatebe, Shinichi Murayama, Toshiya Yonekura, Tomoyuki Hatano, David Richter, Tomomoi Furuya, Saori Kataoka, Kyoko Furuita, Chojiro Kojima, Kazuhiro Shiozaki
[ doi:10.7554/eLife.19594 ]
"Mammalian target of rapamycin (mTOR)," 生体の科学, vol.66, no.5, pp436-437, 2015.10.15
福田 智行, 塩﨑 一裕
"1H, 15N and 13C resonance assignments of the conserved region in the middle domain of S. pombe Sin1 protein.," Biomolecular NMR Assignments, vol.9, pp89-92, Apr. 2015
Saori Kataoka, Kyoko Furuita, Yoshikazu Hattori, Naohiro Kobayashi, Takahisa Ikegami, Kazuhiro Shiozaki, Toshimichi Fujiwara, Chojiro Kojima
[ doi:10.1007/s12104-014-9550-6 ]
"Fission yeast Ryh1 GTPase activates TOR Complex 2 in response to glucose," Cell Cycle, vol.14, no.6, pp848-856, 19 Mar. 2015
Tomoyuki Hatano, Susumu Morigasaki, Hisashi Tatebe, Kyoko Ikeda, Kazuhiro Shiozaki
[ doi:10.1080/15384101.2014.1000215 ]
"Utilization of paramagnetic relaxation enhancements for high-resolution NMR structure determination of a soluble loop-rich protein with sparse NOE distance restraints," Journal of Biomolecular NMR, vol.61, no.1, pp55-64, Jan. 2015
Kyoko Fruita, Saori Kataoka, Toshihiko Sugiki, Yoshikazu Hattori, Naohiro Kobayashi, Takahisa Ikegami, Kazuhiro Shiozaki, Toshimichi Fujiwara, Chojiro Kojima
[ doi:10.1007/s10858-014-9882-7 ]
"Phosphorelay-dependent and -independent regulation of MAPKKK by the Mcs4 response regulator in fission yeast.," Communicative & Integrative Biology, vol.6, no.5, ppe25020, 1 Sep. 2013
Susumu Morigasaki, Kazuhiro Shiozaki
[ doi:10.4161/cib.25020 ]
"Cyclodextrin Complexed [60]Fullerene Derivatives with High Levels of Photodynamic Activity by Long Wavelength Excita-tion," ACS Medicinal Chemistry Letters, vol.4, no.8, pp752-756, 18 Jun. 2013
Atsushi Ikeda, T. Iizuka, N. Maekubo, R. Aono, Junichi Kikuchi, M. Akiyama, T. Konishi, T. Ogawa, Norihiro Ishida, Hisashi Tatebe, Kazuhiro Shiozaki
"A photo-triggerable drug carrier based on cleavage of PEG lipids by photosensitiser-generated reactive singlet oxygen.," Org Biomol Chem., vol.11, pp2567-2570, 28 Apr. 2013
Komeda C, Ikeda A, Junichi Kikuchi, Ishida-Kitagawa N, Tatebe H, Shiozaki K, Akiyama M.
[ doi:10.1039/c2ob27199k ]
"Response regulator-mediated MAPKKK heteromer promotes stress signaling to the Spc1 MAPK in fission yeast.," Mol Biol Cell, vol.24, no.7, pp1083-1092, Apr. 2013
Morigasaki S, Ikner A, Tatebe H, Shiozaki K.
"Rab-family GTPase regulates TOR complex 2 signaling in fission yeast.," Curr. Biol., vol.20, no.22, pp1975-1982, Nov. 2010
H. Tatebe, S. Morigasaki, S. Murayama, Zeng CT, K. Shiozaki
[ doi:10.1016/j.cub.2010.10.026 ]
"Rab-family GTPase regulates TOR complex 2 signaling in fission yeast.," Curr Biol., vol.20, no.22, pp1975, Nov. 2010
H. Tatebe, S. Morigasaki, S. Murayama, Zeng CT, K. Shiozaki
[ doi:10.1016/j.cub.2010.10.026 ]
"Two-component signaling to the stress MAP kinase cascade in fission yeast.," Meth. Enzymol., vol.471, pp279, 2010
S. Morigasaki, K. Shiozaki
[ doi:10.1016/S0076-6879(10)71015-6 ]
"Glycolytic enzyme GAPDH promotes peroxide stress signaling through multistep phosphorelay to a MAPK cascade," Mol. Cell, vol.30, no.1, pp108, Apr. 2008
Morigasaki, S, Shimada, K, Ikner, A, Yanagida, M., Shiozaki, K.
[ doi:10.1016/j.molcel.2008.01.017 ]
"Glycolytic enzyme GAPDH promotes peroxide stress signaling through multistep phosphorelay to a MAPK cascade," Mol. Cell, vol.30, no.1, pp108, Apr. 2008
Morigasaki, S, Shimada, K, Ikner, A, Yanagida, M., Shiozaki, K.
[ doi:10.1016/j.molcel.2008.01.017 ]
受賞
"酵母コンソーシアムフェロー/研究助成," 大隅基礎科学創成財団, 2019.12.16
塩﨑 一裕
"2018年度 生命科学研究助成," 公益財団法人 武田科学振興財団, 2018.7
塩﨑 一裕
"平成28年度「科研費」審査委員表彰," 日本学術振興会, 2016.9.30
塩﨑 一裕
"平成25年度研究助成対象者," 公益財団法人第一三共生命科学研究振興財団, 2013.12.12
塩﨑 一裕
"優秀ポスター賞," 7th International Fission Yeast Meeting, 29 Jun. 2013
Toshiya Yonekura, Kazuhiro Shiozaki
所属学協会
酵母遺伝学フォーラム
The American Society for Cell Biology
日本分子生物学会
資料